Molecular characterization of chronic cutaneous wounds reveals subregion‐ and wound type‐specific differential gene expression
Shola Michelle Richards,
Caroline Gubser Keller,
Robert Kreutzer
et al.
Abstract:A limited understanding of the pathology underlying chronic wounds has hindered the development of effective diagnostic markers and pharmaceutical interventions. This study aimed to elucidate the molecular composition of various common chronic ulcer types to facilitate drug discovery strategies. We conducted a comprehensive analysis of leg ulcers (LUs), encompassing venous and arterial ulcers, foot ulcers (FUs), pressure ulcers (PUs), and compared them with surgical wound healing complications (WHCs). To explo… Show more
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