Molecular characterization of aviadenovirus serotypes and pathogenicity of the identified adenovirus in broiler chickens

Epidemiology, pathology, prevention, and control strategies of inclusion body hepatitis and hepatitis-hydropericardium syndrome in poultry: A comprehensive review

“…The three positive samples (EG101/2018, EG102/2018, and EG103/2018) had nucleotide sequence identities of >97.7% and were genetically more similar to reference strains serotype 2 (FAdV-2). Two isolates out of 15 samples from broilers aged 19–40 days suffering from deaths of 5–10% were positive to FAdV-E 8a in Sharkia governorate, Egypt in the period 2019–2020 ( 54 ).…”

Genomic characterization and pathogenicity of a novel fowl adenovirus serotype 11 isolated from chickens with inclusion body hepatitis in China

“…FAdV-11 is one of the primary causative agents for IBH. In recent years, FAdV-11-associated IBH has been increasingly reported in China and other countries around the world ( Gomis et al, 2006 ; Wilson et al, 2010 ; Nakamura et al, 2011 ; Steer et al, 2015 ; Zhao et al, 2015 ; Morshed et al, 2017 ; Oliver-Ferrando et al, 2017 ; Mohamed et al, 2018 ; Abghour et al, 2019 , 2021 ; El-Tholoth and Abou El-Azm, 2019 ; Huang et al, 2019 ; Mirzazadeh et al, 2020 ; Şahindokuyucu et al, 2020 ; Cizmecigil et al, 2020 ; Hosseini et al, 2020 ; Chen et al, 2020 ; Sabarudin et al, 2021 ; Chitradevi et al, 2021 ; Bertran et al, 2021 ; Mase et al, 2021 ; Lebdah et al, 2022 ; Li et al, 2022 ; Liu et al, 2022 ; Niczyporuk and Kozdruń, 2022 ; Xie et al, 2022 ). Currently, there are no commercially available vaccines against FAdV-11-related IBH.…”

“…Since the first report of IBH in 1963, the disease has spread worldwide. In recent years, outbreaks of IBH have exhibited an increasing trend worldwide and have caused substantial economic losses in many countries ( Helmboldt and Frazier, 1963 ; Gomis et al, 2006 ; Wilson et al, 2010 ; Nakamura et al, 2011 ; Steer et al, 2015 ; Zhao et al, 2015 ; Oliver-Ferrando et al, 2017 ; Morshed et al, 2017 ; Mohamed et al, 2018 ; Huang et al, 2019 ; El-Tholoth and Abou El-Azm, 2019 ; Abghour et al, 2019 , 2021 ; Cizmecigil et al, 2020 ; Chen et al, 2020 ; Hosseini et al, 2020 ; Mirzazadeh et al, 2020 ; Şahindokuyucu et al, 2020 ; Bertran et al, 2021 ; Chitradevi et al, 2021 ; Mase et al, 2021 ; Sabarudin et al, 2021 ; Lebdah et al, 2022 ; Li et al, 2022 ; Liu et al, 2022 ; Niczyporuk and Kozdruń, 2022 ; Xie et al, 2022 ). Inclusion body hepatitis is predominantly observed in broilers and is characterized by a sudden onset of mortality approaching 10 to 30% after 3 to 4 d. A higher mortality rate is observed for birds younger than 3 wk of age.…”