Molecular characterization and immune regulatory, antioxidant, and antiapoptotic activities of thioredoxin domain-containing protein 17 (TXNDC17) in yellowtail clownfish (Amphiprion clarkii)

Enhancing the correlation between in vitro and in vivo experiments in dental implant osseointegration: investigating the role of Ca ions

“…46 Additionally, thioredoxin domain-containing protein 17 is associated with immune regulation, antioxidant functions, and anti-apoptotic roles. 47 MAP2K4 can phosphorylate and activate both c-Jun NH2-terminal kinases (JNKs) and p38 MAP kinases, promoting cell differentiation, proliferation, and apoptosis. 48 In contrast, complement component C9 (C9; 4.35-fold decrease), linked to the activation of the immune response through the complement system pathway, 49 as well as extracellular matrix protein 1 (ECM1; 2.27-fold decrease) and LDL receptor-related protein 4 (LRP4; 4.35-fold decrease), were found in lower quantities on unicCa surfaces.…”

“…46 Additionally, thioredoxin domain-containing protein 17 is associated with immune regulation, antioxidant functions, and anti-apoptotic roles. 47 MAP2K4 can phosphorylate and activate both c-Jun NH2-terminal kinases (JNKs) and p38 MAP kinases, promoting cell differentiation, proliferation, and apoptosis. 48…”

Projected ocean temperatures impair key proteins used in vision of octopus hatchlings

“…Phospholipid-transporting ATPase VD is the catalytic component of the P4-ATPase flippase, which is responsible for the transport of phospholipids to maintain lipid composition of cell membranes (Timcenko et al, 2019). Upregulation Oxidoreductases assist in oxidative damage repair by producing reducing equivalents for antioxidant enzymes (Kültz, 2005), thioredoxins are also part of the oxidoreductase family that serve as electron donors in antioxidant defences (Udayantha et al, 2021).…”

“…Oxidoreductases assist in oxidative damage repair by producing reducing equivalents for antioxidant enzymes (Kültz, 2005), while thioredoxin domain‐containing proteins which are related to thioredoxins are also part of the oxidoreductase family that serve as electron donors in antioxidant defences (Udayantha et al., 2021). Changes in the cellular redox state serves as a trigger of the cellular stress response, thus the activation of these free radical scavenging systems is expected under exposure to thermal stress.…”