Molecular Aspects of Piperine in Signaling Pathways Associated with Inflammation in Head and Neck Cancer
Juliana Prado Gusson-Zanetoni,
Luana Pereira Cardoso,
Stefanie Oliveira De Sousa
et al.
Abstract:Piperine, an active plant alkaloid from black pepper (Piper nigrum), has several pharmacological effects: antioxidant, anti-inflammatory and immunomodulatory, which involves inhibiting molec-ular events associated with various stages of cancer development. The aim of this study was to investigate the molecular mechanisms of action of piperine in relation to its potential anticancer effect on head and neck cancer cells. Parameters related to neoplastic potential, analysis of cyto-kine, protein and gene expressi… Show more
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