Molecular and phenotypic characterization of enterococci isolated from broiler flocks in Turkey

Aslantaş, Özkan

doi:10.1007/s11250-018-01784-z

Cited by 6 publications

(8 citation statements)

References 47 publications

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“…A remarkable diversity of AMR rates has been reported for E. faecalis recovered from different non-clinical settings across the globe. However, in general, resistance to macrolides and tetracycline appears to be ubiquitous in enterococci, likely reflecting the widespread use of these antimicrobials in both human and veterinary medicine (Abriouel et al, 2008;Varela et al, 2013;Aslantas ¸, 2019). Likewise, in the present study, erythromycin was the most prevalent resistance phenotype in E. faecalis across all sources, while higher tetracycline resistance rates were noted in food-producing animals and foods of animal origin.…”

Section: Discussionmentioning

confidence: 45%

“…faecalis isolates, even as in clinical isolates. (Ben Said et al ., 2016; Aslantaş, 2019; Costa et al ., 2019). This bifunctional enzyme essentially confers resistance to all clinically available aminoglycosides except streptomycin, thereby eliminating the synergism between these drugs and cell‐wall‐active agents such as penicillin or vancomycin.…”

Section: Discussionmentioning

confidence: 99%

“…Similar to the present study, the HLGR phenotype in non-clinical E. faecalis of various sources has been most often associated with the presence of aac(6 0 )-Ie-aph(2 00 )-Ia gene, which encodes a bifunctional aminoglycoside-modifying enzyme, showing that this gene is widespread among environmental E. faecalis isolates, even as in clinical isolates. (Ben Said et al, 2016;Aslantas ¸, 2019;Costa et al, 2019). This bifunctional enzyme essentially confers resistance to all clinically available aminoglycosides except streptomycin, thereby eliminating the synergism between these drugs and cell-wall-active agents such as penicillin or vancomycin.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies performed in Brazil, as well as in other countries, have found no resistance or very low resistance rates to penicillin and ampicillin among non‐clinical E . faecalis isolates, similar to that found in the current study and among clinical isolates (Gomes et al ., 2008; Camargo et al ., 2014; Gawryszewska et al ., 2017; Aslantaş, 2019; Zaheer et al ., 2020). Currently, according to the CLSI (2019), ampicillin results may be used to predict susceptibility to amoxicillin and piperacillin, but not to penicillin among non‐β‐lactamase‐producing enterococci.…”

Section: Discussionmentioning

confidence: 99%

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Penicillin‐resistant, ampicillin‐susceptible Enterococcus faecalis isolates are uncommon in non‐clinical sources

Correa

Zanella

Cassiolato

et al. 2022

Environ Microbiol Rep

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This study aimed to investigate whether penicillinresistant, ampicillin-susceptible E. faecalis (PRASEF) isolates are disseminated in non-clinical sources, and to compare the molecular characteristics and antimicrobial resistance (AMR) profile of clinical and non-clinical E. faecalis isolates. Non-clinical samples (n = 280) were collected and 101 E. faecalis isolates were recovered from food (n = 18), faeces of healthy animals (n = 24), water (n = 28) and sewage (n = 31). PRASEF (n = 68) and penicillin-susceptible, ampicillin-susceptible E. faecalis (n = 77) isolates of clinical origin were also evaluated. A significant variety of AMR profiles was observed among non-clinical isolates according to the source. No food isolate exhibited a multidrug resistance (MDR) phenotype different from those of isolates from animal faeces (50.0%) and sewage (38.7%). Overall, the MDR phenotype was more frequent among clinical (56.6%) than non-clinical isolates (22.8%) (p < 0.01). Non-clinical PRASEF isolates (n = 3) were only recovered from hospital sewage. Note that representative clinical and non-clinical PRASEF isolates were grouped in pulsotype A, and belonged to CC9 (clonal complex). In conclusion, E. faecalis isolates exhibiting the unusual penicillin-resistant but ampicillin-susceptible phenotype appeared to be restricted to the hospital environment. Our findings highlight the ability of PRASEF isolates to survive in sewage, which could enable these hospital-adapted lineages to spread to new ecological niches.

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Section: Discussionmentioning

confidence: 45%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Penicillin‐resistant, ampicillin‐susceptible Enterococcus faecalis isolates are uncommon in non‐clinical sources

Correa

Zanella

Cassiolato

et al. 2022

Environ Microbiol Rep

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“…Another study by Abdelhady and Mishra, (2019) and Yamanaka et al (2019) reported a short-lived infection when humans were infected with VRE isolated from animals in an experimental murine model. Molecular studies have also have reported a strong relationship between animals and humans VRE Aslantaş, 2019;ISMB and Talebi, 2019). The presence of plants and wild animals acting as a source of infection indicates that the relationship that exists between the VRE of humans and animals does not show the causal relationship (García-Solache and Rice, 2019).…”

Section: Vre In Animals and Public Health Concernsmentioning

confidence: 95%

Vancomycin-Resistant Enterococcus: Issues in Human Health, Animal Health, Resistant Mechanisms and the Malaysian Paradox

Wada¹,

Harun²,

Yean³

et al. 2019

Adv. Anim. Vet. Sci.

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E nterococcus occur naturally in the surroundings and are an important constituents of the gut microbes in humans and animals (van Schaik and Willems, 2010; Boehm and Sassoubre, 2014). Enterococcus species detected till date are over 50 (Bonacina et al., 2016; Guzman et al., 2016). In human guts, Enterococcus faecalis occur mostly followed by E. faecium while in livestock, E. faecium is the major species followed by E. faecalis, E. cecorum and sometimes E. hirae (Klein, 2003; Guzman et al., 2016). Urinary tract infections, inflammation of the endocardium, and blood infection are linked to Enterococci and these conditions are particularly worse in immunocompromised individuals (Lebreton et al., 2014; Neelakanta et al., 2015). Nosocomial and drug-resistant infections are largely caused by E. faecium and E. faecalis and these pathogens are largely accountable for human vancomycin-resistant enterococci (VRE) infections (van Schaik and Willems, 2010; Leb-reton et al., 2013). The spotlight was beamed on Enterococci as a significant hospital-acquired microbe in regard to their innate resistance to various antibiotics, the rate at which they become highly infectious and the factors responsible for their multidrug resistance (Balli et al., 2014; Bourgeois-Nicolaos et al., 2014; Kristich et al., 2014). Epidemiological reports have continued to implicate VRE in regards to its effect on health, the economy and continuous infection in humans (Byappanahalli et al., 2012; Shaghaghian et al., 2012) following to their earliest documentation in the 80s (Leclercq et al., 1988; Uttley et al., 1988). Though VRE is hardly seen in pets, they rarely cause infection in animals (Willems et al., 2011). Studies have suggested that Enterococcus resistant to vancomycin act as a reservoir and source of resistant genes. This article, therefore, discusses and reviews VRE, its phenotypic and genotypic characteristics, antimicrobial resistance, virulence factors and zoonotic potential. Finally, it sheds review Article Abstract | Enterococcus is a major constituent of the intestinal flora and environment. They are a hardy organism and can survive harsh prevailing environmental factors and hosts. Over time, the constant and heavy usage of antibiotics like vancomycin in treating infection caused by them has resulted in their development of resistance and virulent characteristics. VRE infections in animals are uncommon, and even so in pets. The reverse is, however, the case with human VRE infection. VRE are of great importance in public health, animal and medical health. The adaptability and complexity of the VRE genes have resulted in the appearance of resistant species in a wide range of environment and hosts which will invariably allow the host and environment to act as a reservoir. This article, therefore, discusses and reviews VRE, its phenotypic and genotypic characteristics, antimicrobial resistance, virulence factors and zoonotic potential. Finally, it sheds light on the situation of VRE in Malaysia. This would be the first review to look at V...

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Klebsiella pneumonia carbapenemase (KPC), methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus spp. (VRE) in the food production chain and biofilm formation on abiotic surfaces

Alonso

Queiroz

Gualberto

et al. 2019

Current Opinion in Food Science

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Molecular and phenotypic characterization of enterococci isolated from broiler flocks in Turkey

Cited by 6 publications

References 47 publications

Penicillin‐resistant, ampicillin‐susceptible Enterococcus faecalis isolates are uncommon in non‐clinical sources

Penicillin‐resistant, ampicillin‐susceptible Enterococcus faecalis isolates are uncommon in non‐clinical sources

Vancomycin-Resistant Enterococcus: Issues in Human Health, Animal Health, Resistant Mechanisms and the Malaysian Paradox

Klebsiella pneumonia carbapenemase (KPC), methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus spp. (VRE) in the food production chain and biofilm formation on abiotic surfaces

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