Molecular and Immunological Responses to Food

Turcanu, Victor; Lack, Gideon

doi:10.1128/9781555815721.ch4

Cited by 3 publications

(5 citation statements)

References 250 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Probiotics probably apply a double impact, forestalling the intestinal colonization with pathogen microorganisms [26,8,64]. Or connecting with the gut-related lymphoid tissue (GALT) to forestall provocative reactions and advance a condition of resistance to themselves and potentially to sustenances [65]. The helpful impacts of probiotics are regularly dissimilar and strain-particular [66].…”

Section: Nanoecapsulation and Health Benefits Of Probioticsmentioning

confidence: 99%

Role of Probiotics in Health Improvement: Adaptations, Advantages and their Uses

Pandey

Negi

Sharma

et al. 2018

AFSJ

View full text Add to dashboard Cite

The probiotics especially lactic acid bacteria (LAB) are usually found in human mucous layers, dairy items and on some plant surfaces. These are assumed to be a basic part for nourishment generation and welfare conservation for human beings. There is an expanding fervor for these species to uncover the numerous possible medical advantages related with them. The activities of LAB's are depend on species or strain particular, and rely upon the measure of the number of beneficial microscopic organisms accessible in the gastrointestinal tract. Probiotics are having beneficial effect on human health therefore, with this paper, probiotics are acknowledged as characteristic way to safeguard nourishment and advance welfare. The paper present to survey the brief and current information regarding probiotics in the safeguarding of nourishments, their role in the gastrointestinal tract, and its medical advantages.

show abstract

Section: Nanoecapsulation and Health Benefits Of Probioticsmentioning

confidence: 99%

Role of Probiotics in Health Improvement: Adaptations, Advantages and their Uses

Pandey

Negi

Sharma

et al. 2018

AFSJ

View full text Add to dashboard Cite

show abstract

“…bulgaricus, Saccharomyces boulardii, Streptococcus thermophilus, Bifidobacterium lactis, B. longum, and B. breve. Probiotics presumably exert a dual effect, preventing/decreasing the intestinal colonization with pathogen microorganisms [62], or interacting with the gut-associated lymphoid tissue (GALT) to prevent inflammatory responses and promote a state of tolerance to themselves and possibly to foods [63].…”

Section: Health Benefitsmentioning

confidence: 99%

Probiotic Lactic Acid Bacteria: A Review

Quinto¹,

Jiménez²,

Caro³

et al. 2014

FNS

120

View full text Add to dashboard Cite

Lactic acid bacteria (LAB) play a critical role in food production and health maintenance. There is an increasing interest in these species to reveal the many possible health benefits associated with them. The actions of LAB are species and strain specific, and depend on the amount of bacteria available in the gastrointestinal tract. Consumers are very concerned of chemical preservatives and processed foods. However, products with or processed with LAB are accepted as a natural way to preserve food and promote health. This paper aimed to review the recent data in regard to the role of probiotic LAB in the preservation of foods, in the immunomodulation in the gastrointestinal tract, and in its health benefits.The hypothetical first niche of the ancestral LAB is considered soil and plants and, subsequently, the gut of herbivorous animals [6]. The mammalian intestine is colonized by 100 trillions of microorganisms (called "microbiota") that are essential for health [7] [8]. The transition from soil and plants to the animal gut has three areas of genomic adaptation [9]: resistance to host barriers, adhesion to intestinal cells, and fermentation of some substrates in the gut. The membrane lipid composition is affected by low pH and bile salts. Microarray analysis has shown the expression of a glycerophosphatase in Lactobacillus reuteri after an acid shock, and an increase in the sensitivity to acid in Lactobacillus acidophilus [10]. Extracelullar lipopolysaccharides (LPS) also play a role in the resistance, but it is unclear [6]. The adhesion of LAB to intestinal cells is associated with the peristaltic flow, a good adherence capacity and the presence of mucins to protect and lubricate the epithelial surfaces [11]. Resident intestinal bacteria are able to inhibit the adherence of pathogenic bacteria to intestinal epithelial cells as a result of their ability to increase the production of intestinal mucins [12]. Lactobacillus plantarum increases the levels of expression of the mRNA of some mucins, inhibiting the cell attachment of enteropathogenic Escherichia coli [13] [14]. LAB have access to simple sugars and complex carbohydrates, so bacteria with genes involved in its degradation are probably in better condition to multiply in the gut [6].The resident gastrointestinal microbiota provide a microbial barrier against microbial pathogens [12]. Lactobacillus and Bifidobacterium spp. of human intestinal origin produce antimicrobial substances that are active in vitro and in vivo against enteropathogenic microorganisms involved in diarrhea [15]; both genera have the capacity for interfering with or block the pathogenic process of enteric bacterial pathogens [12]. Strains of Lactobacillus acidophilus, L. johnsonii, L. rhamnosus, L. casei, L. acidophilus, and L. rhamnosus interfere with a wide range of pathogens, such as enteropathogenic Escherichia coli, enterohemorrhagic E. coli, Listeria monocytogenes, Salmonella enterica serovar Typhimurium, and S. flexneri [16]-[22]. Blocking the process of pathogenicity of enteric pat...

show abstract

“…Most of the currently used LAM strains for food products have been isolated from the intestinal microbiota of healthy humans, which are known to have a strong beneficial relationship between the bacterium and its human host. Among them, Lactobacillus and Bifidobacterium are the most frequently used species [45]. Due to these favorable characteristics, commensal or food-fermenting LAB have recently been increasingly investigated for use as live mucosal vectors for the production and in situ delivery of biopharmaceuticals, especially peptide and protein drugs [45,46].…”

Section: Genetically Engineered Food-grade Bacteria As Delivery Systemsmentioning

confidence: 99%

“…Among them, Lactobacillus and Bifidobacterium are the most frequently used species [45]. Due to these favorable characteristics, commensal or food-fermenting LAB have recently been increasingly investigated for use as live mucosal vectors for the production and in situ delivery of biopharmaceuticals, especially peptide and protein drugs [45,46]. The administration of such recombinant microorganisms would significantly lower the production cost of the treatment agents since being live organisms, such vectors would be able to autonomously amplify, produce and deliver the product of interest [46,47].…”

Section: Genetically Engineered Food-grade Bacteria As Delivery Systemsmentioning

confidence: 99%

“…LAB have a long history of use by humans for food production and food preservation, and have earned Generally Recognized as Safe (GRAS) status [43]. LAB can be found in the human GI tract, where they constitute a regular component of the normal microbial flora playing important roles in host gut health (anti-inflammatory, anti-infective and immunomodulatory properties), so called "helpful" bacteria or probiotics [44,45]. Most of the currently used LAM strains for food products have been isolated from the intestinal microbiota of healthy humans, which are known to have a strong beneficial relationship between the bacterium and its human host.…”

Section: Genetically Engineered Food-grade Bacteria As Delivery Systemsmentioning

confidence: 99%

See 1 more Smart Citation

Emerging technologies to achieve oral delivery of GLP-1 and GLP-1 analogs for treatment of type 2 diabetes mellitus (T2DM)

Ma¹,

We²,

Yang³

et al. 2017

Can J Biotech

View full text Add to dashboard Cite

Molecular and Immunological Responses to Food

Cited by 3 publications

References 250 publications

Role of Probiotics in Health Improvement: Adaptations, Advantages and their Uses

Role of Probiotics in Health Improvement: Adaptations, Advantages and their Uses

Probiotic Lactic Acid Bacteria: A Review

Emerging technologies to achieve oral delivery of GLP-1 and GLP-1 analogs for treatment of type 2 diabetes mellitus (T2DM)

Contact Info

Product

Resources

About