Molecular and cellular responses to long-term sound exposure in peled (Coregonus peled)

Abstract

This research examined the impacts of acoustic stress in peled (Coregonus peled Gmelin, 1788), a species commonly cultivated in Russia. This study presents a comparative analysis of the macula sacculi and otoliths, as well as primary hematological and secondary telomere stress responses, in control and sound-exposed peled. The authors measured the effects of long-term (up to 18 days) exposure to a 300 Hz tone at mean sound pressure levels of 176–186 dB re 1 μPa (SPLpk–pk); the frequency and intensity were selected to approximate loud acoustic environments associated with cleaning equipment in aquaculture settings. Acoustic exposure resulted in ultrastructure changes to otoliths, morphological damage to sensory hair cells of the macula sacculi, and a gradual decrease in the number of functionally active mitochondria in the red blood cells but no changes to telomeres. Changes were apparent following at least ten days of acoustic exposure. These data suggest that acoustic exposure found in some aquaculture settings could cause stress responses and auditory damage to peled and, potentially, other commercially important species. Reducing sound levels in fish rearing facilities could contribute to the formation of effective aquaculture practices that mitigate noise-induced stress in fishes.

Accelerated Aging and Age-Related Diseases (CVD and Neurological) Due to Air Pollution and Traffic Noise Exposure

“…Recent studies primarily focused on inflammatory and oxidative stress pathways in response to traffic noise exposure in the context of CVD development (for review see [22,23,131]), while human data linking noise exposure to measures such as telomere length and DNA methylation are generally lacking. Evidence on the association between traffic noise exposure and biological aging mainly arises from animal studies [154][155][156][157][158][159]. Indirect evidence on the role of noise exposure in biological aging is given by human studies demonstrating oxidative DNA damage, a correlate of altered DNA methylation and gene expression, in subjects exposed to occupational [160,161] and traffic noise [114].…”

Sex Associated Effects of Noise Pollution in Stone Sculpin (Paracottus knerii) as a Model Object in the Context of Human-Induced Rapid Environmental Change

“…Particle acceleration was measured using a "Baikal7-HR" triaxial digital recorder with piezoelectric A1638 accelerometers (Moscow, Zelenograd, Russia), as described previously [59]. The amplifiers of the "Baikal-7HR" and the recording elements of the A1638 accelerometers were calibrated with a precision signal generator (G3-110), a source of sinusoidal electrical oscillations with high accuracy and frequency stability in the range of 0.01 Hz-2 MHz.…”

“…Additionally, cell area (S), nuclear area (s), and nuclear-to-cytoplasmic ratio (NCR) were calculated for red blood cells using the formula for the area of an ellipse. Numerical eccentricity (E) was used as a quantitative characteristic of red blood cell shape [59,69]. Red blood cell hemoglobin protein (Hb) was extracted and analyzed using previously tested methods [59].…”

“…Numerical eccentricity (E) was used as a quantitative characteristic of red blood cell shape [59,69]. Red blood cell hemoglobin protein (Hb) was extracted and analyzed using previously tested methods [59].…”

“…A continuous broadband noise with the dominant tonal (narrowband) components from 10 to 500 Hz was selected according to the adequacy of this stimulus in modeling anthropogenic noise pollution [1,5,10]. The duration of the experiment (up to seven days) is long-term [55] and appropriate for the study of the chronic stress responses [56][57][58][59] considering cumulative and synergistic effects. Source levels can range from 150 dB to over 190 dB re 1 µPa at 1 m for the largest vessels [4] and have recently averaged 179 dB [1,6].…”