Molecular analysis and risk factors for nasal colonization with methicillin-resistant Staphylococcus aureus among community individuals attending a Family Health Care Program in Rio de Janeiro, Brazil

Abstract

test were done. Culture was considered as gold standard.Results: Out of 50 immunocompromised patients, 7(14%) were positive for mycobacteria [MTBC 5(10%), MOTT 2(4%)] and 10(20%) were positive for fungi [C. albicans 4(8%), C. glabrata 4(8%) and C. tropicalis 2(4%)]. Out of 50 apparently immunocompetant patients (diseased control), 4(8%) were positive for mycobacteria [MTBC 3(6%), MOTT 1(2%)] and 3(6%) were positive for fungi [C. albicans 2(4%) and C. tropicalis 1(2%)]. Sensitivity and specificity were 71.42%, 90.69% of Ziehl-Neelsen stain, 88%, 100% of Lowenstein Jensen culture, 57%, 100% of PCR for Mycobacteria, 80%, 100% respectively for wet mount for fungi.Conclusion: Incidence of mycobacterial/fungal infection in immunocompromised patients is more then to immunocompetent individuals and with immunocompromised conditions, urinary tract infection should be screened for mycobacterial and fungal pathogens.