Molar root-incisor malformation: considerations of diverse developmental and etiologic factors

Wright, J. Timothy; Curran, Alice E.; Kim, Kyoung Jin; Yang, Yeon Mi; Nam, Soon Hyeun; Shin, Teo Jeon; Hyun, Hong‐Keun; Kim, Young Jae; Lee, Sang Hoon; Kim, Jung Wook

doi:10.1016/j.oooo.2015.08.024

Cited by 31 publications

(114 citation statements)

References 41 publications

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“…Permanent central incisors were affected in 35.6% of patients, primary second molars in 39.1% of patients, and permanent canines in 6.9% of patients. Primary first molars were affected in one patient, and the permanent lateral incisors and permanent right first pre‐molars were involved in another patient …”

Section: Resultsmentioning

confidence: 99%

“…Brusevold et al reported that the molars in two of their cases demonstrated demarcated opacities. These malformations most commonly involve the permanent first molars; however, primary second molars, permanent incisors, and rarely other teeth have been reported to also be affected . In the cases that showed more extensive involvement of other teeth besides the primary second molars and permanent incisors, it is important to note that the first permanent molars were still affected in all of these cases .…”

Section: Discussionmentioning

confidence: 97%

“…The exact aetiology of this condition is unknown; however, the fact that the root malformations are limited to isolated teeth suggests that a non‐genetic, environmental factor related to past medical history could be the cause . Moreover, no specific genetic mutation has been identified to date.…”

Section: Discussionmentioning

confidence: 99%

“…Later, Lee et al described 12 cases of this dental abnormality, which they named molar‐incisor malformation (MIM). Since its initial description, several reports and series have documented additional MIM cases involving the permanent first molars, permanent central incisors, and also other teeth …”

Section: Introductionmentioning

confidence: 99%

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Molar‐incisor malformation: Eight new cases and a review of the literature

Vargo

Reddy

Costa

et al. 2019

Int J Paed Dentistry

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Background Molar‐incisor malformation (MIM) is a recently described dental abnormality. While MIM mimics dentin dysplasia, it presents in a localized pattern. Furthermore, it is speculated that MIM is caused by significant early‐life medical history. Aim The purpose of this study is to present a series of MIM cases and compare the findings with the literature. Design An extensive search of all published cases of MIM in the English‐language literature was conducted. Additionally, an institutional review board‐approved retrospective search was performed within the University of Florida oral pathology biopsy service archives. Radiographic consultation cases were also included. Cases lacking radiographs were excluded. Results Seventy‐nine cases were identified in the literature, and eight cases were identified in our retrospective search. All but one case involved the permanent first molars. The average age at diagnosis was 9 years. Many patients reported significant early‐life medical histories. Conclusions MIM usually affects the permanent first molars and may be linked to early‐life medical conditions or interventions. Oral healthcare providers, especially paediatric dentists, should be aware of MIM to avoid misdiagnosing it as dentin dysplasia. Long‐term follow‐up studies with thorough medical history documentation are essential to understand the pathogenesis and aetiology and to create treatment guidelines.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Molar‐incisor malformation: Eight new cases and a review of the literature

Vargo

Reddy

Costa

et al. 2019

Int J Paed Dentistry

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show abstract

“…A newly described condition called Molar Incisor Root Malformation (Figure 7) primarily affects root development of the first permanent molars but can affect other teeth including the permanent incisors and second primary molars. (20) The primary care dentist should coordinate treatment with the orthodontist as these cases may require extraction of the first permanent molars as there long term prognosis can be quite guarded.…”

Section: Developmental Defects Of Dentinmentioning

confidence: 99%