Molar incisor hypomineralization (<scp>MIH</scp>): prevalence and degree of severity in a Mexican pediatric population living in an endemic fluorosis area

Sosa-Soto, Joselyn; Padrón-Covarrubias, Ana Isabel; Márquez-Preciado, Raúl; Ruiz-Rodríguez, Socorro; Pozos‐Guillén, Amaury; Pedroza-Uribe, Isaac Murisi; Bayardo-González, Rubén Alberto; Garrocho‐Rangel, Arturo

doi:10.1111/jphd.12446

Cited by 7 publications

(2 citation statements)

References 38 publications

(102 reference statements)

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“…In this study, a supervised machine learning model was constructed by incorporating a variety of factors that impact the occurrence of MIH in endemic fluorosis regions. The nomograms showed that sex had no influence on occurrence, which is consistent with previous studies ( Yi et al, 2021 ; Sosa-Soto et al, 2022 ). Exposure to low-quality shallow underground water did not increase the likelihood of developing MIH.…”

Section: Discussionsupporting

confidence: 91%

Study on machine learning of molar incisor hypomineralization in an endemic fluorosis region in central China

et al. 2023

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Objectives: The aim of the present study was to develop a machine learning model to predict the risk of molar incisor hypomineralization (MIH) and to identify factors associated with MIH in an endemic fluorosis region in central China.Methods: A cross-sectional study was conducted with 1,568 schoolchildren from selected regions. The clinical examination included an investigation of MIH based on the European Academy of Paediatric Dentistry (EAPD) criteria. In this study, supervised machine learning (e.g., logistic regression) and correlation analysis (e.g., Spearman correlation analysis) were used for classification and prediction.Results: The overall prevalence of MIH was 13.7%. The nomograph showed that non-dental fluorosis (DF) had a considerable influence on the early occurrence of MIH and that this influence became weaker as DF severity increased. We examined the association between MIH and DF and found that DF had a protective correlation with MIH; the protective effect became stronger as DF severity increased. Furthermore, children with defective enamel were more likely to experience caries, and dental caries were positively correlated with MIH (OR = 1.843; 95% CI: 1.260–2.694). However, gender, oral hygiene, and exposure to poor-quality shallow underground water did not increase the likelihood of developing MIH.Conclusions: DF should be considered a protective factor within the multifactorial etiology of MIH.

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Section: Discussionsupporting

confidence: 91%

Study on machine learning of molar incisor hypomineralization in an endemic fluorosis region in central China

et al. 2023

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“…Almost all of the included studies reported that molars were more affected than incisors which agrees with the results from other populations [ 35 – 37 ]. However, variation exists within the included studies according to the most affected dental arch.…”

Section: Discussionsupporting

confidence: 86%

Prevalence of Molar-incisor hypomineralization in Iranian children – A systematic review and narrative synthesis

et al. 2022

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Introduction Molar-incisor hypomineralization is a developmental defect of enamel with clinical features vary from demarcated opacities to severe tissue breakdown which calls for considerable preventive and interceptive measures. The aim of this article was to systematically review the literature on the prevalence of MIH in Iran and highlight the condition in Iranian children. Materials and Methods A systematic search of literature was conducted in Scopus, Pubmed, Ovid, Embase, Web of Science, and Google-Scholar as well as national Iranian database and digital archives of dental schools from the beginning of 2000 to the end of 2021 for published and unpublished studies. Data from cross-sectional, cohort, and case-control studies on prevalence of molar-incisor hypomineralization among 6–13-year-old children was gathered, using the following MeSH terms and keywords and their Persian equivalents: Prevalence, Hypomineralisation, Hypomineralization, MIH, “molar incisor”, “molar-incisor”, “cheese molars”, “Hypomineralised first permanent molars”, “Hypomineralized first permanent molars”, “developmental defects of enamel”, “enamel developmental defects”, Iran*. Methodological quality and the risk of bias of quantitative studies was assessed using a modified version of Newcastle-Ottawa Scale. Due to the considerable clinical and statistical heterogeneity of the included studies, pooling of data through meta-analysis was not possible. Therefore, a descriptive synthesis of data was performed. Results Fifteen cross-sectional studies with a total number of 12011 participants were included in the systematic review. The prevalence of MIH ranged from 5.1% to 25.6%. All of the included studies were at a moderate risk of bias (NOS of 4-6). The lowest prevalence of MIH was reported in Kerman (5.14%) and the highest in Tehran (25.6%). Substantial methodological, clinical and statistical heterogeneity was observed. Conclusion This is the first study to systematically review the available literature on MIH prevalence in Iran. However, the present review has some limitations such as limited number of included studies, large heterogeneity of the research, and moderate quality of included studies. Further high-quality research is warranted.

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The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis

Lopes

Machado

Mascarenhas

et al. 2021

Sci Rep

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Molar-Incisor Hypomineralization (MIH) is a qualitative defect of enamel of unknown etiology, affecting one or more permanent molars and may include incisors. This condition is a clinical challenge and its prevalence is still uncertain given the recent increase in research. Thus, we aimed to comprehensively estimate the overall prevalence of MIH and associated characteristics. This systematic review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). We searched articles using PubMed, MEDLINE, CENTRAL, Web of Science, SciELO, LILACS and TRIP databases, until July 2021. Heterogeneity and publication bias were computed via I2 test statistics and Egger’s significance test, respectively. Random-effects meta-analysis of prevalence were processed. We used the Strength of Recommendation Taxonomy [SORT] to grading the strength of evidence. Overall, 116 observational studies were included, with one study with moderate methodological quality and the remaining of high methodological quality. Subgroup analysis confirmed an influence of not using the 2003 MIH case definition (p = 0.0066). The pooled prevalence of MIH was 13.5% (95% CI 12.0–15.1, I2 = 98.0%). Affected incisors were seen in 36.6% (95% CI 30.0–43.7, I2 = 92.5%) of the cases. Lastly, the prevalence of hypomineralization of the second primary molars was observed in 3.6% of the MIH cases (95% CI 1.9–6.8, I2 = 96.3%). America was the continent with highest prevalence (15.3, 95% CI 12.8–18.3, p < 0.001, I2 = 96.3%) and Asia had the lowest prevalence (10.7, 95% CI 8.5–13.5, p < 0.001, I2 = 98.7%), however no continental differences were found. Sample size and year of publication were slight contributing factors to the heterogeneity in the analysis. Overall, these results were classified with a SORT A recommendation.

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Molar incisor hypomineralization (MIH): prevalence and degree of severity in a Mexican pediatric population living in an endemic fluorosis area

Cited by 7 publications

References 38 publications

Study on machine learning of molar incisor hypomineralization in an endemic fluorosis region in central China

Study on machine learning of molar incisor hypomineralization in an endemic fluorosis region in central China

Prevalence of Molar-incisor hypomineralization in Iranian children – A systematic review and narrative synthesis

The prevalence of molar-incisor hypomineralization: a systematic review and meta-analysis

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