Molar Changes with a Normal Viable Fetus: A Case Report

Farazestanian, Marjaneh; Maleki, Asieh; Bolandi, Somayeh; Yousefi, Zohreh; Hasanzadeh, Malihe; Shirinzadeh, Laya; Kamandi, S H

doi:10.18502/jfrh.v14i3.4675

Cited by 3 publications

(3 citation statements)

References 8 publications

(6 reference statements)

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“…Zilberman Sharon et al 10 and Farazestanian et al 11 proffered insights resonating with our observations, while Uemura et al 12 and Loza et al 13 extolled the virtues of avantgarde diagnostic modalities.…”

Section: Discussionsupporting

confidence: 82%

Twin pregnancy: Live fetus with complete hydatidiform molar—A case report

Yared,

Dahrouj,

El Hajjar

et al. 2023

SAGE Open Medical Case Reports

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Gestational trophoblastic disease encompasses a range of lesions, each culminating in varied clinical manifestations. Among these, the simultaneous occurrence of molar changes within the placenta and a viable fetus remains a particularly elusive and challenging presentation, posing intricate dilemmas for obstetricians. In this article, we delineate a distinct case involving a 21-year-old woman with a history of consanguineous marriage. She was referred from Médecins Sans Frontières to the Rafic Hariri University Hospital during her 19th week of gestation. With an unremarkable medical history and uncomplicated previous pregnancies, her presentation to the Rafic Hariri University Hospital was punctuated by symptoms of premature labor. Clinical evaluations revealed ruptured membranes, a fetus-positioned breech, and discernible complications tied to the placental morphology. Given these clinical findings, a decision was made in favor of a Cesarean delivery. Prior to this, the patient had been administered corticosteroids and tocolytics. Subsequent delivery produced a live male infant at 34 + 5 gestational days, and further assessment unveiled a complete molar pregnancy. The coexistence of a viable fetus alongside a complete molar pregnancy is an infrequently documented phenomenon, underlining the clinical significance of this case. A comprehensive literature survey reinforced the exceptional nature of our findings. Postpartum, both the mother and neonate were monitored for a month, ensuring their well-being. This case accentuates the paramountcy of prompt and precise diagnostic interventions when faced with atypical presentations. It further underscores the imperative for obstetricians to possess nuanced expertise in confronting the intricate challenges posed by gestational trophoblastic disease, ensuring optimal maternal and neonatal outcomes.

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Section: Discussionsupporting

confidence: 82%

Twin pregnancy: Live fetus with complete hydatidiform molar—A case report

Yared,

Dahrouj,

El Hajjar

et al. 2023

SAGE Open Medical Case Reports

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“…According to histopathology and microscopic features of the placenta, moles are classified into complete and partial mole. 3 at 9 weeks and 18 weeks pregnancy; report were normal. At 27 weeks, ultrasonography and E HCG was done outside NICRH in private chamber report was 27 weeks pregnancy with suggestive of hydatidiform mole; N.B: a large hyper echogenic soft tissue mass interposed with multiple tiny cystic spaces is seen in the cavity near to placenta size about 9.3x9.6 cm and serum E HCG was 3, 23,280 IU/L at 7months pregnancy (but normal value 3000-15000 IU/L).…”

Section: Introductionmentioning

confidence: 83%

Molar pregnancy with a co-exist normal viable fetus and successful pregnancy outcome: a case report

Hossain,

Anjuman,

Mahmud

et al. 2023

Bangladesh Med Res Counc Bull

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Background: Co-existence of a hydatidiform mole with a normal fetus is extremely rare and is considered as a high risk pregnancy. Methods: It was an observational study conducted during July 2020 to march 2021 Case report: A 23 year old primigravida, referred with a diagnosis of 27 weeks pregnancy with gestational choriocarcinoma. She was booked patient. USG report at 9 weeks with a single gestational sac and single fetal pole. Her complains were lower abdominal pain and brownish vaginal discharge. Thoroughly evaluated the patient to exclude distal metastasis. Serum Beta HCG was 3,23,280 IU/L. USG and fetal MRI report were single graved fetus, no anomaly detected and a large hyper echogenic soft tissue mass (10*7cm) interposed with multiple tiny cystic spaces near to placenta. Diagnosis was 28 weeks pregnancy with partial mole and high rising β HCG level. Proper counseling, the pregnancy was continued as per the patient’s desire. The pregnancy was closely monitored with serial serum β HCG, and USG. Spontaneously labour pain start at 36 weeks pregnancy and delivered a live baby per vaginally at 36 weeks with near normal Apgar score. The placenta with molar tissue was sent for histopathological examination. The histopathologically confirmed partial mole with normal placenta. Beta HCG was 20,000 ml/L at 7 days and normal at 8 weeks after delivery. Close surveillance for 6 months. After 6 month follow-up, both mother and development of her baby are alright. Conclusion: The diagnosis, management and monitoring of this condition will remain challenging because of its rarity. Though the general trend is to terminate pregnancy with coexistent mole in anticipation of complications, under close surveillance, optimal outcomes can be achieved. Bangladesh Medical Res Counc Bull 2022; 48(3): 249-253

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“…It is developed according to the review of literature and based on the available and cited evidences. [9,19,20,26,29,30,[36][37][38][39].…”

Section: Discussionmentioning

confidence: 99%

Partial hydatidiform mole with alive pre-term foetus: a case report

Bensissaid¹,

Kerbi²,

Djaou³

et al. 2023

Ital J Gynaecol Obstet

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Background. Partial hydatiform mole (PHM) with an alive foetus is exceptional (0,005% to 0,01% of all pregnancies).Case presentation. here we report a case of a 33-year-old multiparous woman. The diagnosis of PHM was suspected late, at 28 weeks gestational age. After a spontaneous initiation of the labour, at 34 th weeks gestational age, she gave birth to a normal living baby. Histopathology of the placenta confirmed the PHM while the karyotype of the new-born was 46XX. The level of beta chorionic gonadotropin (βHCG) was negative after three weeks post-delivery. Currently, the child is two years old with normal psycho-motor development.Conclusions. despite the multiple and serious complications that may arise in patients with PHM, a favourable outcome is possible.

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Molar Changes with a Normal Viable Fetus: A Case Report

Cited by 3 publications

References 8 publications

Twin pregnancy: Live fetus with complete hydatidiform molar—A case report

Twin pregnancy: Live fetus with complete hydatidiform molar—A case report

Molar pregnancy with a co-exist normal viable fetus and successful pregnancy outcome: a case report

Partial hydatidiform mole with alive pre-term foetus: a case report

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