One of the challenges of climate change in the building sector is related to the durability of materials, i.e., the resistance to degradation due to weathering over time. The durability of building components can be assessed through long-term natural outdoor climate exposure or appropriate accelerated climate aging in the laboratory. SINTEF Research Centre owns a climate simulator apparatus to perform aging tests according to the Nordtest method NT Build 495:2000. The aim of this article is to show the results from an accelerated climatic aging test performed on three different configurations of a structural insulated panel (SIP), which is characterized by waste-based core materials. The samples were tested for one month, corresponding to about one year of natural outdoor climate exposure. The results from the test performed in the climate simulator include information on the sample changes occurring during the analyzed period, together with the scale of such changes and the time of occurrence. Therefore, the test results are qualitative and based on the fact that a change in the performance properties of the samples corresponds to a change in their appearance during the test. This includes, for instance, signs of degradation, such as cracks, loss of gloss, or delamination.