Mohs Micrographic Surgery

Wong, Emily Y.; Axibal, Eileen; Brown, Mariah

doi:10.1016/j.fsc.2018.08.002

Cited by 44 publications

(46 citation statements)

References 113 publications

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“…In this study, 7 baseline patients' characteristics, recurrence and clinical outcomes were not significantly different between MMS techniques. Comparing both techniques, in terms of performance and implementation in daily practice, frozen MMS (or direct/fresh Mohs) has the main advantage of reducing surgical times as it implies immediate microscopic examination of surgical margins 22,23 and completion of surgery with definite wound closure at the same surgical process 24‐26 …”

Section: Resultsmentioning

confidence: 99%

Mohs micrographic surgery in dermatofibrosarcoma protuberans: Rate and risk factors for recurrence in a prospective cohort study from the Spanish Registry of Mohs Surgery (REGESMOHS) and review of the literature

Nieto‐Benito

Ciudad-Blanco

Sanmartín-Jiménez

et al. 2021

Experimental Dermatology

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Characterization of patients, surgery procedures and the risk factors for dermatofibrosarcoma protuberans (DFSP) recurrences is poorly defined. In this study, we aimed to describe the demographics, tumor characteristics and interventions of DFSP treated with Mohs micrographic surgery (MSS) to determine the rate and risk factors for recurrence. Data were collected from REGESMOHS, a nationwide prospective cohort study of patients treated with MMS in Spain. From July 2013 to February 2020, 163 patients with DFSP who underwent MMS were included. DFSP was mostly located on trunk and extremities. Recurrent tumors had deeper tumor invasion and required higher number of MMS stages. Paraffin MMS was the most frequently used technique. Overall recurrence rate was 0.97 cases/100 person‐years (95% IC = 0.36–2.57). No differences were found in epidemiological, tumor, surgery characteristics or surgical technique (frozen or paraffin MMS [p = 0.6641]) in terms of recurrence. Median follow‐up time was 28.6 months with 414 patient‐years of follow‐up. In conclusion, we found an overall low recurrence rate of DFSP treated with MMS. None of the studied risk factors, including MMS techniques, was associated with higher risk for recurrence.

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Section: Resultsmentioning

confidence: 99%

Mohs micrographic surgery in dermatofibrosarcoma protuberans: Rate and risk factors for recurrence in a prospective cohort study from the Spanish Registry of Mohs Surgery (REGESMOHS) and review of the literature

Nieto‐Benito

Ciudad-Blanco

Sanmartín-Jiménez

et al. 2021

Experimental Dermatology

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“…The process is repeated so that the edges expand only on the positive margin until completely clean edges are obtained, while at the same time healthy tissue is spared. Therefore, it is necessary for the Mohs surgeon to be an educated dermatopathologist at the same time [9]. This method achieves the best results in the treatment of non-melanoma skin cancers, especially in regions where it is important to preserve function and/or cosmetic results, such as the maxillofacial region [10].…”

Section: Discussionmentioning

confidence: 99%

Locally advanced basal cell carcinoma of the auricle and parotid region: A case report

et al. 2021

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Skin cancers are the most common malignant tumors in general. The most significant risk factor is exposure to UV radiation. They mainly occur in the head and neck region, and the majority of about 80% are basal cell carcinomas. Surgery is standard treatment of uncomplicated basal cell carcinomas, but a multidisciplinary approach is necessary in advanced cases. The case report refers to a patient with locally advanced recurrent basal cell carcinoma with primary tumor localization in the right auricle and parotid region in 2012 when primary surgery was performed. Due to the local recurrence, amputation of the right auricle and trepanation of the mastoid process was done in November 2018, and after that, radiation therapy of a recurrent tumor in the area of the trepanation cavity was applied. In the course of follow-up so far, there is good local control, without signs of toxicity. The case report points to the importance of a multidisciplinary approach and the role of radiotherapy in the treatment and control of advanced basal cell carcinoma of this region.

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“…This procedure can be continued until the cancer-free area is achieved. Dr. Mohs named his new surgery technique "Chemosurgery," which states the chemical fixation of surgically excised tissue [18,19]. Over time, the chemosurgery method gained popularity as a treatment option, but it was associated with certain disadvantages such as more than half of a day require to fix the tissue by zinc chloride, the ability of zinc chloride paste to cause significant swelling and pain requiring hospitalization, and duration of each chemosurgery stage (almost a day) resulting in multiple-day treatment.…”

Section: Mmsmentioning

confidence: 99%

“…In most cases, restoration of the defect after the surgery can be done on the same day. However, MMS has disadvantages such as long surgical treatment period, inability to perform the surgery on patients who cannot tolerate surgery under local anesthesia, and difficulty in clearing margins for aggressive tumors involving deep structures, such as bone or parotid gland [18]. Complication like difficulties in homeostasis is associated with the MMS [10].…”

Section: Mmsmentioning

confidence: 99%

A Brief Review of Treatment Modalities for Non-Melanoma Skin Cancer

Shah

2021

Asian J Pharm Clin Res

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NMSC (Non-melanoma skin cancer) is the most commonly occurring malignancy in Caucasians. Out of all diagnosed NMSC cases, 95% of the cases are of basal cell carcinoma and squamous cell carcinoma. The therapeutic approaches to cure or ultimately rescue the skin area affected by NMSC include surgical methods, photodynamic therapy, radiation therapy, immunotherapy, and chemotherapy. This article aims to provide a brief overview of the preliminary mechanism of action, clinical studies, advantages, and disadvantages of currently available treatment modalities.

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Mohs Micrographic Surgery

Cited by 44 publications

References 113 publications

Mohs micrographic surgery in dermatofibrosarcoma protuberans: Rate and risk factors for recurrence in a prospective cohort study from the Spanish Registry of Mohs Surgery (REGESMOHS) and review of the literature

Mohs micrographic surgery in dermatofibrosarcoma protuberans: Rate and risk factors for recurrence in a prospective cohort study from the Spanish Registry of Mohs Surgery (REGESMOHS) and review of the literature

Locally advanced basal cell carcinoma of the auricle and parotid region: A case report

A Brief Review of Treatment Modalities for Non-Melanoma Skin Cancer

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