Mohs Micrographic Surgery Concordance Between Mohs Surgeons and Dermatopathologists

Semkova, Kristina; Mallipeddi, R.; Robson, Alistair; Παλαμάρας, Ιούλιος

doi:10.1111/dsu.12320

Cited by 16 publications

(11 citation statements)

References 14 publications

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“…At the EMC, additional reviews were performed by a pathologist, which increased costs. Other studies show that the rate of slides interpreted in concordance by a MMS surgeon and a pathologist is high (95–100%) . These studies conclude that MMS surgeons are able to review MMS slides as well as pathologists do.…”

Section: Discussionmentioning

confidence: 66%

Additional review of Mohs slides to optimize Mohs micrographic surgery

et al. 2015

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Section: Discussionmentioning

confidence: 66%

Additional review of Mohs slides to optimize Mohs micrographic surgery

et al. 2015

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“… 29 Studies carried out in different countries have demonstrated a 99% degree of agreement between Mohs surgeon and dermatopathologist in the evaluation of clear margins. 30 , 31 , 32 , 33 In the present study, the agreement of the aggressiveness of the BCCs was assessed in the preoperative biopsy; the kappa score demonstrated a substantial agreement between the Mohs surgeon and the dermatopathologist. This variation in the classification of subtypes has already been evaluated in other studies, such as that by Genders et al, in which two dermatopathologists evaluated the MMS slides, with substantial agreement, similar to the present study.…”

Section: Discussionmentioning

confidence: 75%

Comparison of basal cell carcinoma subtypes observed in preoperative biopsy and Mohs micrographic surgery

Cerci

Kubo

Werner

2020

Anais Brasileiros de Dermatologia

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Background The treatment of basal cell carcinoma depends on its histological subtype. Therefore, a biopsy should be performed before definitive treatment. However, as the biopsy is only a sample of the tumor, it does not always shows every histological subtype present in the neoplasm. Few studies have compared the histological findings of biopsies with the findings of Mohs micrographic surgery. By evaluating the totality of the peripheral margins, in addition to sampling large tumor areas, this technique provides a more representative amount of tissue than preoperative biopsy. Objectives a) Determine the agreement between the histological subtype of basal cell carcinoma from punch biopsy and the findings of Mohs surgery; b) To assess, among the discordant cases, the prevalence of non-aggressive tumors in the preoperative biopsy that were reclassified as aggressive by Mohs surgery. Methods Retrospective analysis of 79 cases of basal cell carcinomas submitted to punch biopsy and subsequent Mohs surgery. Results The agreement between the classification of the subtypes in the biopsy and in Mohs surgery was 40.5%. Punch biopsy was able to predict the most aggressive basal cell carcinoma growth pattern in 83% of cases. Study limitations Retrospective nature, sample size, and biopsies performed by different professionals. Conclusions The agreement between the histopathological subtypes of basal cell carcinoma as seen in preoperative biopsy and Mohs surgery was low. However, preoperative biopsy presented good accuracy (83%) in detecting aggressive histopathological subtypes.

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“…Previous studies show high interpersonal agreement between Mohs surgeons and pathologists (95–99%) on BCC presence . These studies overestimate the reliability of diagnosis from Mohs slides because they report concordance rates instead of κ values.…”

Section: Discussionmentioning

confidence: 93%

“…1,2 Previous studies show high interpersonal agreement between Mohs surgeons and pathologists (95-99%) on BCC presence. [17][18][19][20][21][22] These studies overestimate the reliability of diagnosis from Mohs slides because they report concordance rates instead of j values. In contrast to these studies, we oversampled difficult Mohs slides, which resulted in an underestimated level of agreement.…”

Section: Discussionmentioning

confidence: 99%

Reliability of diagnosis from Mohs slides: interpersonal and intrapersonal agreement on basal cell carcinoma presence and histological subtype

Lee¹,

Ching²,

Nasserinejad³

et al. 2016

Br J Dermatol

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Mohs Micrographic Surgery Concordance Between Mohs Surgeons and Dermatopathologists

Abstract: The high rate of agreement in this study confirms that adequately trained MMS surgeons have sufficient expertise and training for accurate and precise frozen sections interpretation.

Cited by 16 publications

References 14 publications

Additional review of Mohs slides to optimize Mohs micrographic surgery

Additional review of Mohs slides to optimize Mohs micrographic surgery

Comparison of basal cell carcinoma subtypes observed in preoperative biopsy and Mohs micrographic surgery

Reliability of diagnosis from Mohs slides: interpersonal and intrapersonal agreement on basal cell carcinoma presence and histological subtype

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