Mohs' kirurgi ved basalcellekarsinom i ansiktet

Roscher, Ingrid; Brevig, Trine; Mørk, Gro; Helsing, Per; Gjersvik, Petter

doi:10.4045/tidsskr.11.0343

Cited by 15 publications

(16 citation statements)

References 43 publications

(37 reference statements)

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“…In recent years, a variety of AuNP-based assays have been developed to detect small organic molecules that play important roles in the human body, such as dopamine, 113 cocaine, 114 ATP, 115,116 glucose, 117 Cys, [118][119][120][121] and other biothiols (Table 3). [122][123][124] Dopamine, an important neurotransmitter of nervous systems, was monitored using unmodified AuNPs due to the hydrogen bonding interactions between the hydroxyl groups on dopamine that absorbed onto surfaces of unmodified AuNPs, thus leading to aggregation of AuNPs. 113 Based on unmodified AuNPs, the Fan group presented a novel design to detect ATP by using the anti-ATP aptamer, which possesses a highly selective affinity for ATP.…”

Section: Assays For Small Organic Moleculesmentioning

confidence: 99%

Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

2011

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In recent years, gold nanoparticles (AuNPs) have drawn considerable research attention in the fields of catalysis, drug delivery, imaging, diagnostics, therapy and biosensors due to their unique optical and electronic properties. In this review, we summarized recent advances in the development of AuNP-based colorimetric and fluorescent assays for ions including cations (such as Hg(2+), Cu(2+), Pb(2+), As(3+), Ca(2+), Al(3+), etc) and anions (such as NO(2)(-), CN(-), PF(6)(-), F(-), I(-), oxoanions), and small organic molecules (such as cysteine, homocysteine, trinitrotoluene, melamine and cocaine, ATP, glucose, dopamine and so forth). Many of these species adversely affect human health and the environment. Moreover, we paid particular attention to AuNP-based colorimetric and fluorescent assays in practical applications.

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Section: Assays For Small Organic Moleculesmentioning

confidence: 99%

Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

2011

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“…[13] Mohs surgery is resource-demanding, but lowers the risk of recurrence and can be cost-effective if is considered in BCC with an aggressive growth pattern on the face. [14]…”

Section: Therapeutic Approaches At Treatment Of Bccmentioning

confidence: 99%

Clinical variants, stages, and management of basal cell carcinoma

Dourmishev

Rusinova²,

Botev

2013

Indian Dermatol Online J

104

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Basal cell carcinoma (BCC) is the most common paraneoplastic disease among human neoplasms. The tumor affects mainly photoexposed areas, most often in the head and seldom appears on genitalia and perigenital region. BCC progresses slowly and metastases are found in less than 0.5% of the cases; however, a considerable local destruction and mutilation could be observed when treatment is neglected or inadequate. Different variants as nodular, cystic, micronodular, superficial, pigment BCC are described in literature and the differential diagnosis in some cases could be difficult. The staging of BCC is made according to Tumor, Node, Metastasis (TNM) classification and is essential for performing the adequate treatment. Numerous therapeutic methods established for treatment of BCC, having their advantages or disadvantages, do not absolutely dissolve the risk of relapses. The early diagnostics based on the good knowledge and timely organized and adequate treatment is a precondition for better prognosis. Despite the slow progress and numerous therapeutic methods, the basal cell carcinoma should not be underestimated.

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“…Glutathione (GSH) is an important thiolated tripeptide and endogenous antioxidant and exists widely in the intracellular environment. − The level of GSH is associated with many diseases including aging and cancer . A number of methods have been developed to interrogate the GSH level inside cells, including luminescence analysis, fluorometry, colorimetry, and electrochemistry . The photoelectrochemical (PEC) method, a recently developed detection approach, uses light and electricity energy for the sensor excitation and detection, respectively, thus enabling efficient reduction of some undesired background noise and increasing sensitivity .…”

mentioning

confidence: 99%

Photoelectrochemical Detection of Glutathione by IrO₂–Hemin–TiO₂ Nanowire Arrays

et al. 2013

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We have developed sensitive detection of glutathione using the IrO2-hemin-TiO2 nanowire arrays. Single-crystalline TiO2 nanowires are synthesized by a hydrothermal reaction, followed by surface functionalization of ~3 nm thick hemin and ~1-2 nm diameter IrO2 nanoparticles. The IrO2-hemin-TiO2 nanowire arrays offer much enhanced photocurrent with ∼100% increase compared to the pristine TiO2 nanowires and allow for label-free, real-time, sensitive photoelectrochemical detection of glutathione. The sensitivity achieved is ~10 nM in buffer, comparable to or better than most of the existing glutathione detection methods. Furthermore, cell extracts containing glutathione are robustly detected, with ~8000 cells/mL for HeLa cells and ~5000 cells/mL for human embryonic kidney 293T cells. This nanowire PEC sensor assay exhibits excellent selectivity and stability, suggesting a potential detection platform for analyzing the glutathione level in biosamples.

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Mohs' kirurgi ved basalcellekarsinom i ansiktet

Cited by 15 publications

References 43 publications

Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

Clinical variants, stages, and management of basal cell carcinoma

Photoelectrochemical Detection of Glutathione by IrO₂–Hemin–TiO₂ Nanowire Arrays

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Mohs' kirurgi ved basalcellekarsinom i ansiktet

Cited by 15 publications

References 43 publications

Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

Gold nanoparticles for the colorimetric and fluorescent detection of ions and small organic molecules

Clinical variants, stages, and management of basal cell carcinoma

Photoelectrochemical Detection of Glutathione by IrO2–Hemin–TiO2 Nanowire Arrays

Contact Info

Product

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About

Photoelectrochemical Detection of Glutathione by IrO₂–Hemin–TiO₂ Nanowire Arrays