Möglichkeiten der Prophylaxe von arteriellen Restenosen mit Dexamethason - eine In-vitro-Studie an humanen aortalen glatten Muskelzellen

Abstract

Depending on the dose applied, incubation with dexamethasone results in a significant growth reduction of cultured haSMC, which may be due to a drug induced G1-phase block. Dexamethasone also reduces the clonogenic activity as well as the migratory ability of cultured haSMC.