MOF-derived Co3O4@Co-Fe oxide double-shelled nanocages as multi-functional specific peroxidase-like nanozyme catalysts for chemo/biosensing and dye degradation

Copper-Sensitized “Turn On” Peroxidase-Like Activity of MMoO4 (M = Co, Ni) Flowers for Selective Detection of Aquatic Copper Ions

“…The optimal pH, temperature, and reaction time for the NiMoO 4 –Cu 2+ system were 4.0 (Figure S4C), 30 °C (Figure S4D), and 15 min (Figure S4B), respectively. In general, CoMoO 4 , like most other reported peroxidase mimics, exhibits catalytic activity because of the redox cycle reaction. ,, Under acidic conditions, especially within the range of 3–4, the redox cycles inside the nanozyme, as well as the electron transfer between the nanozymes and catalytic substrates can be obviously accelerated by hydrogen ions (H + ). , As an artificial co-enzyme, copper ions (Cu 2+ ) conform to the above principle of the oxidation–reduction cycles so that CoMoO 4 –Cu 2+ could reach a higher activity in the pH range of 3–4. To illustrate the optimal temperature, the adsorption interaction of MMoO 4 with Cu 2+ at different temperatures was investigated.…”

Nanozyme-Participated Biosensing of Pesticides and Cholinesterases: A Critical Review

“…A classic example was reported by Yan's group, where a colorimetric assay composed of Fe 3 O 4 MNPs with HRP-like activity, AChE and CHO was developed for OPs and nerve agent sensing [47]. Subsequently, a series of nanomaterials with peroxidase-like activity were explored for such a ternary colorimetric system [53][54][55][56][57]. Compared to that of natural HRP, all the artificial mimics are easier to get desired catalytic performance via purposeful activity modulation.…”

“…As a matter of fact, multiple interactions between the sulfydryl group of TCh and nanozymes often coexist in a ChE-nanozyme cascade system [53,87,88]. Ni et al developed a colorimetric sensing platform for AChE activity and its inhibitor based on peroxidase-like Prussian blue nanocubes, AChE, ATCh, H 2 O 2 and TMB [87].…”

“…In their system, the generated TCh could cheat with active Fe 3+ in the nanozyme, and it also chemically reduced the product TMBox to TMB again. Chen et al prepared Co 3 O 4 @Co-Fe oxide double-shelled nanocages (DSNCs) with specific peroxidase-like activity for ChE detection [53]. In the AChE-Co 3 O 4 @Co-Fe oxide DSNCs system, TCh not only re-reduced TMBox to TMB, but also blocked the active sites of Co 3 O 4 @Co-Fe oxide DSNCs by coordinating with their metal centers.…”

A sensitive biomimetic enzyme-linked immunoassay method based on Au@Pt@Au composite nanozyme label and molecularly imprinted biomimetic antibody for histamine detection

“…Gomaa developed a new nano-ELISA for the detection of Trichinellosis by mixing horseradish peroxidase (HRP) with a certain ratio AuNPs to form Aunano probes as signal amplification (Gomaa, 2020). However, the catalyst activity for most of the nanozyme is lower than the natural enzyme (Chen et al, 2020;He et al, 2018). How to improve the catalyst activity of the nanozyme is of great significance.…”