Abstract:Seleno-compounds have gained a significant consideration due to their efficiency as chemotherapeutic agents. The aim of the current work was to elucidate the impact of "Ebselen" on Diethylnitrosamine-initiated hepatocarcinogenesis in male albino rats. Hepatocellular carcinoma was initiated with oral supplementation of diethylnitrosamine (DEN] (15mg⁄ kg body-weight) for 2 months. Ebselen (5mg⁄ kg body-weight) was orally given to rats for 2 months after DEN-administration. Biochemical analysis includes assessmen… Show more
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