Modulation of the Urethral
Pressure by High-Frequency
Block Stimulus in Dogs

Ishigooka, Manabu; Hashimoto, Tohru; Sasagawa, Isoji; Izumiya, Ken; Nakada, Teruhiro

doi:10.1159/000475313

Cited by 35 publications

(16 citation statements)

References 16 publications

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“…Another attempt to utilise the methods of Solomonow to produce a block of sphincter activity was performed by ISHIGOOKA, et al (1994). A monophasic waveform was used, with a constant amplitude of 10 V and a constant phase duration of 200 gs.…”

Section: Medical and Biological Engineering And Computing 2004 Vol 42mentioning

confidence: 99%

“…isolated conditions in frog, rat, cat and dog models (CATTELL and GERARD, 1935;REBOUL and ROSENBLUETH, 1939;TANNER, 1962;Woo and CAMPBELL, 1964;SOLOMONOW et al, 1983;SOLOMONOW, 1984;BOWMAN and MCNEAL, 1986;ZHOU et al, 1987;BARATTA et al, 1989; RATTAY, 1990;HASSOUNA et al, 1992;ISHIGOOKA et al, 1994;LI et al, 1995;SAWAN et al, 1996;SHAKER et al, 1998;WILLIAMSON, 1999;ABDEL-GAWAD et al, 2001). However, the mechanism for this type of block is not known, and the reported results appear to be contradictory in many cases, in particular, it is not clear whether high-frequency nerve conduction block is due to a fatigue mechanism (HAsSOUNA et al, 1992) or to a true conduction block in the nerve membrane.…”

mentioning

confidence: 99%

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Nerve conduction block utilising high-frequency alternating current

Kilgore

Bhadra

2004

Med. Biol. Eng. Comput.

245

307

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High-frequency alternating current (AC) waveforms have been shown to produce a quickly reversible nerve block in animal models, but the parameters and mechanism of this block are not well understood. A frog sciatic nerve/gastrocnemius muscle preparation was used to examine the parameters for nerve conduction block in vivo, and a computer simulation of the nerve membrane was used to identify the mechanism for block. The results indicated that a 100% block of motor activity can be accomplished with a variety of waveform parameters, including sinusoidal and rectangular waveforms at frequencies from 2 kHz to 20 kHz. A complete and reversible block was achieved in 34 out of 34 nerve preparations tested. The most efficient waveform for conduction block was a 3-5 kHz constant-current biphasic sinusoid, where block could be achieved with stimulus levels as low as 0.01 microCphase(-1). It was demonstrated that the block was not produced indirectly through fatigue. Computer simulation of high-frequency AC demonstrated a steady-state depolarisation of the nerve membrane, and it is hypothesised that the conduction block was due to this tonic depolarisation. The precise relationship between the steady-state depolarisation and the conduction block requires further analysis. The results of this study demonstrated that high-frequency AC can be used to produce a fast-acting, and quickly reversible nerve conduction block that may have multiple applications in the treatment of unwanted neural activity.

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Section: Medical and Biological Engineering And Computing 2004 Vol 42mentioning

confidence: 99%

mentioning

confidence: 99%

Nerve conduction block utilising high-frequency alternating current

Kilgore

Bhadra

2004

Med. Biol. Eng. Comput.

245

307

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“…Based on the work by Tanner [1962], a number of investigators have reported conduction block in nerve with high-frequency stimulation [Solomonow, 1984;Bowman and McNeal, 19861. The use of a high-frequency block in urology has been investigated by Ishigooka et al [1994]. In acute canine experiments they placed two bipolar electrodes on each pudendal nerve.…”

Section: Additional Measures To Prevent Sphincter Contractionmentioning

confidence: 99%

Urinary bladder control by electrical stimulation: Review of electrical stimulation techniques in spinal cord injury

et al. 1997

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“…A revisable peripheral nerve block by electrical currents could be very useful in many clinical applications. For example, blocking pudendal nerve conduction during micturition could reduce urethral pressure and improve voiding efficiency for spinal cord injured patients [5], [6]. This application of electrical stimulation can be used for treatment of tinnitus.…”

Section: Introductionmentioning

confidence: 99%

Evaluating High-Frequency Nerve Conduction Block for Tinnitus Treatment Using SEF Model

Hajebi

2010

2010 4th International Conference on Bioinformatics and Biomedical Engineering

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Tinnitus is defined as "unwanted auditory perception of internal origin, usually localized, and rarely heard by others. Tinnitus is a sensibly experienced ringing sensation in the auditory system, which occurs without the presence of an actual auditory stimulation". Nowadays many researchers focused on finding a method for treatment of tinnitus. Although they report many different treatments, none of them are reported to be the certain cure of tinnitus. As tinnitus is caused by spontaneous activity of nerve fibers that sometimes its source cannot be detected, using means of electric stimulation for blocking auditory nerve fiber can be useful method for preventing tinnitus to be felt by patients. In this paper we focused on this point and tried to illustrate different aspects of that. First of all, we developed a computational model of fiber based on SEF fiber model. After we studied effects of different parameters such as wave shape, frequency, amplitude, fiber diameter and its distance from electrode, on experiment result and finally discussed result of computer simulation and come to conclusion.

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Modulation of the Urethral Pressure by High-Frequency Block Stimulus in Dogs

Cited by 35 publications

References 16 publications

Nerve conduction block utilising high-frequency alternating current

Nerve conduction block utilising high-frequency alternating current

Urinary bladder control by electrical stimulation: Review of electrical stimulation techniques in spinal cord injury

Evaluating High-Frequency Nerve Conduction Block for Tinnitus Treatment Using SEF Model

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