Modulation of the immune system of chickens a key factor in maintaining poultry production—a review

Wlaźlak, Sebastian; Pietrzak, Elżbieta; Biesek, Jakub; Dunisławska, Aleksandra

doi:10.1016/j.psj.2023.102785

Cited by 12 publications

(7 citation statements)

References 192 publications

(211 reference statements)

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“…Ketidaknyataan seluruh perlakuan pada penelitian diduga karena telah tercukupinya oksigen dalam tubuh ayam untuk ditransportasikan guna memenuhi kebutuhan fisiologis dan metabolik ayam broiler. Pemberian sinbiotik memberikan perubahan metabolik dan fisiologis pada ayam broiler sehingga meningkatkan pertumbuhan dan metabolisme lanjutan yang berguna untuk perkembangan ternak (Wlaźlak et al 2023).…”

Section: Hasil Dan Pembahasanunclassified

Penambahan Mikroenkapsulasi Sinbiotik (Bacillus subtilis dan Mannan oligosakarida) pada Pakan terhadap Profil Hematologi Ayam Broiler

Alditya Putri Yulinarsari,

Niati Ningsih,

Nur Muhamad

2024

JINTP

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This study aimed to evaluate the effect of microencapsulation synbiotics by combining Bacillus subtilis as a probiotic and Mannan oligosaccharide as a prebiotic on the haematological profile of broilers. A total of 100 broiler chickens were used in this research. The experimental design used was a Completely Randomized Design (CRD) with 4 four treatments, namely P0: Feed + 0% Synbiotic Microencapsulation; P1: Feed + 0.25% Synbiotic Microencapsulation; P2: Feed + 0.50% Synbiotic Microencapsulation; P3: Feed + 0.75% Synbiotic Microencapsulation. The treatment was repeated 5 five times and each replication consisted of 5 broilers. Research variables carried out through laboratory testing include the number of haemoglobin, erythrocytes, hematocrit, and the erythrocyte index, namely MCV (Mean Corpuscular Volume); MCH (Mean Corpuscular Hemoglobin); MCHC (Mean Corpuscular Hemoglobin Concentration). The results showed that there was no significant difference between treatments regarding the addition of synbiotics (B. Subtilis and Mannan oligosaccharide) on the haematological profile of broilers. The conclusion of the research was that the addition of synbiotic microencapsulation (Bacillus subtilis and Mannan oligosaccharide) in feed has the potential to support growth and maintain physiological conditions but is considered not capable of maintaining a stable level of broiler health. Key words: Bacillus subtilis, broiler, Mannan oligosaccharide, synbiotic

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Section: Hasil Dan Pembahasanunclassified

Penambahan Mikroenkapsulasi Sinbiotik (Bacillus subtilis dan Mannan oligosakarida) pada Pakan terhadap Profil Hematologi Ayam Broiler

Alditya Putri Yulinarsari,

Niati Ningsih,

Nur Muhamad

2024

JINTP

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“…Parameters such as leukocyte counts and serum protein levels provide valuable insights into immune status. Additionally, specific assays like ELISA and PCR enable the detection of antibodies or pathogens associated with immunosuppressive diseases [4]. Observation of clinical signs serves as a primary method for gauging immunosuppression in poultry.…”

Section: Evaluation Techniques For Assessing and Monitoring Immunosup...mentioning

confidence: 99%

“…Consumers increasingly expect poultry products to be sourced from farms that prioritize animal welfare, underscoring the interconnectedness between animal welfare, immune health, and consumer preferences. Ultimately, by prioritizing both poultry welfare and immune health, agricultural practitioners not only safeguard the well-being of their flocks but also meet the expectations of conscientious consumers and uphold the integrity of the poultry industry [4]. Consumers are increasingly attuned to the conditions under which their food is produced, demanding transparency, accountability, and adherence to humane standards.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Welfare Aspects of Immunosuppression in Poultry Farming

Alispahic,

Softic,

Kustura

et al. 2024

Veterinary Medicine and Science

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Immunosuppression refers to a condition in which the body’s immune system becomes weakened or suppressed, making them more susceptible to infections, diseases and other health problems. Immunosuppression in poultry can be caused by a variety of factors, including infectious activity (viruses, bacteria, parasites, and fungi), environmental stress, malnutrition, and poor management. Viruses have the most dominant immunosuppressive effect on the poultry population, especially infectious bursitis virus, infectious anemia virus and Marek’s disease virus. Immunosuppression in poultry can have significant consequences on their health, welfare, and overall productivity. The biggest losses in poultry production are reflected in reduced growth and performance of individuals, reduced egg production and shell quality, increased morbidity and mortality rates, and greater susceptibility of immunocompromised individuals to secondary infections. Effective management strategies are key to minimizing the impact of immunosuppression in poultry. Biosecurity measures, strict hygiene protocols, immunoprophylaxis, control, and reduced transport of poultry and people, adequate diet, and correct husbandry and housing conditions are some of the factors that result in prevention and/or solvation of this problem.

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“…First, secondary (acquired) immunodeficiencies have been noted in birds, which are characterized by a decrease in immune system function and resistance to various infections [ 7 , 8 ]. The main task of the immune system is to recognize and eliminate foreign substances of antigenic nature [ 9 ]. This function is performed, on the one hand, with the help of innate immunity and, on the other hand, adaptive (acquired).…”

Section: Introductionmentioning

confidence: 99%

Cytokine and immunoglobulin profiles of Arbor Acres broiler chickens at different stages of physiological development

Lebedev,

Kazakova,

Marshinskaia

2024

Vet World

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Background and Aim: Modern scientific research focuses on a detailed study of the immune system, the mechanisms of immunosuppression, and the search for an effective means to restore disturbed immune homeostasis in farm animals. The present study examined the cytokine and immunoglobulin (Ig) profiles of healthy broiler chickens during physiological development. Materials and Methods: Arbor Acres broilers (n = 28) were used in the study to achieve this objective. The immune status of broiler chickens was assessed on 7, 14, 28, and 42 days of age, including serum levels of cytokines, Igs, and lysozyme by enzyme immunoassay. Results: We observed a decrease in the efficiency of immune system functioning of birds with increasing age. The most pronounced immunological deficiency in the body of broiler chickens is noted at the age of 7–14 days, which is associated with immaturity of the immune system and is characterized by the fact that non-specific humoral and specific cellular defense factors are at a rather low level. The levels of lysozyme, interleukin (IL)-2, IL-10, and IgA in blood serum at this age were minimal; starting from 28 days of age, there is a specific humoral immune deficiency, which is compensated by strengthening of cellular defense factors. The serum level of IgY intensively decreases against the background of an increase of lysozyme, IL-2, IL-4, and IL-10. Conclusion: During postnatal ontogenesis, the immune system of broiler chickens undergoes dynamic changes that have an age direction and phase character. Changes in the immune system may affect immunocompetence, disease susceptibility, and, consequently, productivity. Keywords: immunity, immunodeficiency, inflammation, poultry.

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Modulation of the immune system of chickens a key factor in maintaining poultry production—a review

Cited by 12 publications

References 192 publications

Penambahan Mikroenkapsulasi Sinbiotik (Bacillus subtilis dan Mannan oligosakarida) pada Pakan terhadap Profil Hematologi Ayam Broiler

Penambahan Mikroenkapsulasi Sinbiotik (Bacillus subtilis dan Mannan oligosakarida) pada Pakan terhadap Profil Hematologi Ayam Broiler

Clinical and Welfare Aspects of Immunosuppression in Poultry Farming

Cytokine and immunoglobulin profiles of Arbor Acres broiler chickens at different stages of physiological development

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