Modulation of resting‐state brain functional connectivity by exposure to acute fourth‐generation long‐term evolution electromagnetic field: An fMRI study

Wei, Yiwen; Yang, Jiayi; Chen, Zhiye; Wu, Tongning; Lv, Bin

doi:10.1002/bem.22165

Cited by 12 publications

(6 citation statements)

References 42 publications

(66 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed, on one hand EEG allows to measure neuronal processes in the time frame in which these processes occur, but on the other it suffers from poor spatial resolution making difficult the location of the brain areas generating the neuronal activity measured on the scalp (Michel and Brunet 2019). For example, a functional magnetic resonance imaging study revealed that exposure to fourth-generation Long-Term Evolution Electromagnetic field seems to induce changes in the amplitude of spontaneous low frequency fluctuations in the temporal gyrus and modulate brain functional intra-and inter-regional connectivity, including temporal brain regions (Wei et al 2019).…”

Section: Discussionmentioning

confidence: 99%

Human resting-state EEG and radiofrequency GSM mobile phone exposure: the impact of the individual alpha frequency

Wallace

Yahia-Chérif

Gitton

et al. 2021

International Journal of Radiation Biology

View full text Add to dashboard Cite

Purpose. With the extensive use of mobile phone (MP) several studies have been realized to investigate the effects of radiofrequency electromagnetic fields (RF-EMF) exposure on brain activity at rest via electroencephalography (EEG), and the most consistent effect has been seen on the alpha band power spectral density (PSD). However, some studies reported an increase or a decrease of the PSD, while others showed no effect. It has been suggested that these differences might partly be due to a variability of the physiological state of the brain between subjects. So, the aim of this study was to investigate the alpha band modulation, exploring the impact of the alpha band frequency ranges applied in the PSD analysis.Materials & Methods. Twenty-one healthy volunteers took part to the study with a doubleblind, randomized and counterbalanced crossover design, during which eyes-open (EO) and eyes-closed (EC) resting-state EEG was recorded. The exposure system was a sham or a real GSM (global system for mobile) 900 MHz MP (pulse modulated at 217 Hz, mean power of 250 mW and 2 W peak, with a maximum specific absorption rate of 0.70 W/kg on 1 g tissue).The experimental protocol presented a baseline recording phase without MP exposure, an exposure phase during which the exposure system was placed against the left ear, and the postexposure phase without MP. EEG data from baseline and exposure phases were analyzed and PSD was computed for the alpha band in the fixed range of 8-12 Hz and for the individual alpha band frequency range (IAF).Results. Results showed a trend in decrease or increase of EEG power of both alpha oscillations during exposure in relation to EC and EO recording conditions, respectively, but not reaching statistical significance. Findings did not provide evidence for a different sensitivity to RF-EMF MP related to individual variability in the frequency of the alpha band. Conclusion.In conclusion, these results did not show alpha band activity modulation during resting-state under RF-EMF. It might be argued the need of a delay after the exposure in order 3 to appreciate an EEG spectral power modulation related to RF-EMF exposure.

show abstract

Section: Discussionmentioning

confidence: 99%

Human resting-state EEG and radiofrequency GSM mobile phone exposure: the impact of the individual alpha frequency

Wallace

Yahia-Chérif

Gitton

et al. 2021

International Journal of Radiation Biology

View full text Add to dashboard Cite

show abstract

“…Signals averaged over several ICs were computed for connectivity and may conceal the change in terms of individual IC. Wei et al ( 37 ) detected that acute LTE-EMF exposures modulated both localized intraregional connectivity and interregional connectivity with the other voxels were computed. It evaluated the brain modulation on the level of voxels and without the conception of network structure.…”

Section: Discussionmentioning

confidence: 99%

No Alteration Between Intrinsic Connectivity Networks by a Pilot Study on Localized Exposure to the Fourth-Generation Wireless Communication Signals

Yang

Liu

Zhou

et al. 2022

Front. Public Health

Self Cite

View full text Add to dashboard Cite

Neurophysiological effect of human exposure to radiofrequency signals has attracted considerable attention, which was claimed to have an association with a series of clinical symptoms. A few investigations have been conducted on alteration of brain functions, yet no known research focused on intrinsic connectivity networks, an attribute that may relate to some behavioral functions. To investigate the exposure effect on functional connectivity between intrinsic connectivity networks, we conducted experiments with seventeen participants experiencing localized head exposure to real and sham time-division long-term evolution signal for 30 min. The resting-state functional magnetic resonance imaging data were collected before and after exposure, respectively. Group-level independent component analysis was used to decompose networks of interest. Three states were clustered, which can reflect different cognitive conditions. Dynamic connectivity as well as conventional connectivity between networks per state were computed and followed by paired sample t-tests. Results showed that there was no statistical difference in static or dynamic functional network connectivity in both real and sham exposure conditions, and pointed out that the impact of short-term electromagnetic exposure was undetected at the ICNs level. The specific brain parcellations and metrics used in the study may lead to different results on brain modulation.

show abstract

“…The effect of an acute 30 min head exposure to a 2.573 GHz LTE signal on the global neuronal networks activity was recently explored in healthy human volunteers. Using resting state functional resonance magnetic imaging, it was observed that the LTE exposure induced alterations in spontaneous slow frequency fluctuations and in intraregional or interregional connectivities (Lv et al 2014;Wei et al 2019;Yang et al 2021). Under similar exposure conditions, electroencephalographic analyses indicated reduced spectral powers and interhemispheric coherences in the alpha and beta bands (Yang et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Exposure to 1800 MHz LTE electromagnetic fields under proinflammatory conditions decreases the response strength and increases the acoustic threshold of auditory cortical neurons

Souffi

Lameth

Gaucher

et al. 2022

Preprint

View full text Add to dashboard Cite

Increased needs in mobile phone communications have raised successive generations (G) of wireless technologies, which could differentially affect biological systems. We have assessed how a single 2h head-only exposure to a 4G long term evolution (LTE)-1800 MHz electromagnetic field (EMF) impacts on the microglial space coverage and the electrophysiological neuronal activity in the primary auditory cortex (ACx) in rats submitted to an acute neuroinflammation induced by lipopolysaccharide. The mean specific absorption rate in the ACx was 0.5 W/kg. Multiunit recording revealed that LTE-EMF triggered reduction in the response strength to pure tones and to natural vocalizations, together with an increase in acoustic threshold in the low and medium frequencies. Iba1 immunohistochemistry showed no change in the area covered by microglia cell bodies and processes. In healthy rats, the same LTE-exposure induced no change in response strength and acoustic threshold. Our data indicate that an acute neuroinflammation sensitize neuronal responses to LTE-EMF, which leads to an altered processing of acoustic stimuli in the ACx.

show abstract

Modulation of resting‐state brain functional connectivity by exposure to acute fourth‐generation long‐term evolution electromagnetic field: An fMRI study

Cited by 12 publications

References 42 publications

Human resting-state EEG and radiofrequency GSM mobile phone exposure: the impact of the individual alpha frequency

Human resting-state EEG and radiofrequency GSM mobile phone exposure: the impact of the individual alpha frequency

No Alteration Between Intrinsic Connectivity Networks by a Pilot Study on Localized Exposure to the Fourth-Generation Wireless Communication Signals

Exposure to 1800 MHz LTE electromagnetic fields under proinflammatory conditions decreases the response strength and increases the acoustic threshold of auditory cortical neurons

Contact Info

Product

Resources

About