Modulation of RANKL and Osteoprotegerin in Adolescents Using Orthodontic Forces

Hamman, Nathan Reed

doi:10.21007/etd.cghs.2010.0125

Cited by 3 publications

(4 citation statements)

References 78 publications

(93 reference statements)

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“…A current study investigating the change in volume of GCF exudate during canine retraction reported a slight, but non-significant, increase GCF levels (Dannan et al 2009). Most recently, a study with similar methodology to ours reported a significant increase in GCF volumes during orthodontic force application, as well as a significant decrease towards baseline GCF levels following force removal (Hamman et al 2009). …”

Section: Crevicular Fluidsupporting

confidence: 69%

“…Toygar (2008) et al found OPG in the GCF of teeth undergoing orthodontic retraction and teeth not undergoing orthodontic mechanics. A recent study with a similar experimental protocol by Hamman et al (2009) reported only 21.6% RANKL and 2.92% OPG detectability, meaning that most of the samples had concentrations below the level of detectability.…”

Section: Rankl and Opg Detectabilitymentioning

confidence: 95%

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RANKL and Osteoprotegerin Levels in Response to Orthodontic Forces

Hart¹

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Section: Crevicular Fluidsupporting

confidence: 69%

Section: Rankl and Opg Detectabilitymentioning

confidence: 95%

RANKL and Osteoprotegerin Levels in Response to Orthodontic Forces

Hart¹

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“…No experimental data are available on the effect of strontium on root resorption to compare with this study. The lesser occurrence of root resorption in the experimental sides can be explained by the action mechanism of strontium through its ability to modulate RANKL/OPG balancing system (25) which is important in regulating RANKL and OPG in periodontal tissues and is therefore critical to regulate root resorption during orthodontic tooth movement (16,26) .…”

Section: Discussionmentioning

confidence: 99%

“…According to Kim et al, (13) ; Tyrovola et al, (14) ; Seifi and Jessri (15) ; and Hamman (16) the RANKL/OPG balancing system is important in regulating RANKL and OPG in periodontal tissues and for osteoclastogenesis and is therefore critical to regulate bone remodeling during orthodontic tooth movement as well as root resorption.…”

Section: Introductionmentioning

confidence: 99%

The Effect of local injection of strontium on inhibition and repair of orthodontically induced root resorption in rats (An experimental study)

Al-Duliamy¹,

Saloom²,

Shebeeb³

et al. 2018

MDJ

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Background: Strontium (Sr) is an alkaline earth trace metal cation that has a highaffinity for hydroxyapatite. This study aimed to examine the histological effect oflocally injected strontium (Sr) on prevention and repair of induced root resorptionof rat molar subjected to orthodontic tooth movement.Materials and Methods: Eighteen ten-week- old male Wister rats were randomlydivided into two groups of nine animals for two experiments. In both experiments;uniform standardized expansive springs were used to move maxillary first molarsbuccally for three weeks and then removed. In experiment No.1, at the time ofspring placement, 0.25 ml of the strontium chloride solution at a concentration 240mg/ml was injected at the sub-periosteum of the buccal side of the maxillary leftfirst molar which was the experimental side. On other hand, 0.25 ml of distilledwater was injected at the sub-periosteum of the buccal side of the right maxillaryfirst molar which was the control side. The injections repeated every other day forthree weeks whereas in experiment 2 it was begun at the day of spring removal andrepeated every other day for another three weeks. After that the animals werescarified humanly and biopsies were taken for histological examination.Results: In experiment 1 the side injected with strontium showed statisticallysignificant lesser root resorption than control side, while in experiment two thestrontium injected side showed significantly more repair.Conclusion: Results of the study suggested that local injection of strontium caninhibit root resorption process and enhance repair.

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Oral Manifestations, Biochemical, and IL-6 Analysis of Saliva in Epileptic Patients under Treatment

Al-Aswad¹,

Fawzi²

2018

MDJ

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Background: From the ancient Greek (epilepsia). Seizure is common and diverse setof chronic neurological disorders characterized by seizures.Patients and Methods: The sample population comprised 10 epilepsy patients and 10persons with no history of systemic disease, oral manifestation was recorded aswell as saliva samples were taken. The IL-6, alkaline phosphatase and totalsalivary proteins had been measured.Results: The most frequent oral manifestation was gingival hyperplasia 85.7%, anddry mouth 75%, increased level of IL-6 and total salivary proteins in epilepsypatients receiving treatment, when comparing the level of alkaline phosphatase,slightly decreased in study group, with no statistical significance.Conclusion: In addition to the systemic effects of antiepileptic medication, and oraleffects, including saliva composition and oral manifestation was recorded also.Therefore epileptic patients are at an increased risk of developing dry mouth,gingival hyperplasia, and alteration in saliva composition compared with healthsubjects..

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Modulation of RANKL and Osteoprotegerin in Adolescents Using Orthodontic Forces

Cited by 3 publications

References 78 publications

RANKL and Osteoprotegerin Levels in Response to Orthodontic Forces

RANKL and Osteoprotegerin Levels in Response to Orthodontic Forces

The Effect of local injection of strontium on inhibition and repair of orthodontically induced root resorption in rats (An experimental study)

Oral Manifestations, Biochemical, and IL-6 Analysis of Saliva in Epileptic Patients under Treatment

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