Modulation of oxidative status in the red muscle of Carassius auratus gibelio exposure to silicon quantum dots

Petrache, S.N.; Stanca, Loredana; Radu, Mihaela; Serban, Andreea Iren; Sima, Cornelia; Zarnescu, Otilia; Costache, Marieta; Dinischiotu, Anca

doi:10.1016/j.toxlet.2011.05.766

Cited by 1 publication

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“…Moreover, it was shown to be a sensitive experimental model for studying the impact of organic and inorganic pollutants (Moon et al, 2006;Falfushynska et al, 2014;Khan et al, 2014). There is a great number of studies devising biomarkers for responses to and toxicity of various organic and inorganic pollutants in this species (Shao et al, 2010;Petrache et al, 2011;Kreitsberg et al, 2013). However, no comprehensive report that solely reveals biomarkers responses to environmental Pb 2+ in Crucian carp is available.…”

Section: Introductionmentioning

confidence: 99%

Organ-specific antioxidant defenses and FT-IR spectroscopy of muscles inCrucian carp (Carassius auratus gibelio) exposed to environmental Pb2+

Khan¹,

Liu²,

Hong³

et al. 2015

Turk J Biol

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Being a nonessential element, lead (Pb 2+ ) can be toxic in trace amounts for freshwater fish. The present study was designed to evaluate the induction of oxidative stress, tissue-specific antioxidant response, acetyl cholinesterase (AchE) activities, and biochemical content of muscle in Crucian carp (Carassius auratus gibelio) after 96 h of acute exposure and 21 days of chronic exposure to various environmental concentrations (5, 10, and 30 µg L -1 ) of waterborne Pb 2+ . The results indicated that exposure to 10 and 30 µg L -1 Pb 2+ significantly altered the activities of catalase, superoxide dismutase, and glutathione peroxidase in different tissues, while malondialdehyde content increased in a time-and concentration-dependent manner. Inhibition of AchE after chronic exposure also confirmed a generalized neurotoxic stress. Fourier transform infrared spectroscopy revealed mild changes in the structure of proteins and lipids, whereas the integrated biomarker response indices signified the liver, kidneys, and gills as the responsive organs to environmental Pb 2+ exposure.

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