“…The issue of increased "wanting" or "craving" following cocaine administration, which has also been characterized as "priming" (de Wit, 1996), has been the subject of follow-up investigations. Unlike the preclinical literature, the findings of these clinical investigations were mixed; whereas a subset of studies replicated the results reported by Jaffe and colleagues (Fischman, Foltin, Nestadt, & Pearlson, 1990;Jaffe et al, 1989;Kosten et al, 1992;Nann-Vernotica, Donny, Bigelow, & Walsh, 2001;Sofuoglu, Brown, Babb, Pentel, & Hatsukami, 2000a,b;Walsh, Haberny, & Bigelow, 2000;Ward, Haney, Fischman, & Foltin, 1997a,1997bWard, Haney, Fischman, & Foltin, 1998), others did not (De La Garza, Foltin & Haney, 2000;Foltin et al, 2003;Romach et al, 1999;Sofuoglu, Pentel, Bliss, Goldman, & Hatsukami, 1999). To our knowledge, the clinical phenomenon of priming has not been addressed by a formal literature review.…”