Modulation of intracortical inhibition and excitation in agonist and antagonist muscles following acute strength training

Mason, Joel; Howatson, Glyn; Frazer, Ashlyn K.; Pearce, Alan J.; Jaberzadeh, Shapour; Avela, Janne; Kidgell, Dawson

doi:10.1007/s00421-019-04203-9

Cited by 12 publications

(11 citation statements)

References 69 publications

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“…Therefore, acute modifications in the efficacy of the inhibitory intracortical circuits could be more related to the level of peripheral fatigue attained during the training session than to the intensity of training . Also, other ST characteristics could influence the acute modulation of the responses to TMS after a single session of ST. For example, dynamic ST paced by an audible cue leads to increased CSE accompanied by increased ICF and reduced intracortical inhibition, whereas internally paced ST did not . This greater acute neural modulation could be related to higher auditory afferent input from the auditory cortex synchronized with the activation of corticospinal neurons during muscle contractions, which lead to an increased synaptic efficacy according to Hebbian principles .…”

Section: Discussionmentioning

confidence: 95%

“…15 Also, other ST characteristics could influence the acute modulation of the responses to TMS after a single session of ST. For example, dynamic ST paced by an audible cue leads to increased CSE accompanied by increased ICF and reduced intracortical inhibition, whereas internally paced ST did not. 30 This greater acute neural modulation could be related to higher auditory afferent input from the auditory cortex synchronized with the activation of corticospinal neurons during muscle contractions, which lead to an increased synaptic efficacy according to Hebbian principles. 31 Thus, it seems that the acute neural modulation after an acute ST session could be affected by different ST characteristics such as intensity, level of peripheral fatigue, the type of contraction or the strategy of pacing the movement, or even the volume of exercise.…”

Section: Trained Sidementioning

confidence: 99%

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Training intensity‐dependent increases in corticospinal but not intracortical excitability after acute strength training

Colomer‐Poveda

Hortobágyi

Keller

et al. 2019

Scandinavian Med Sci Sports

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The purpose of this study was to determine whether the increases in corticospinal excitability (CSE) observed after one session of unilateral isometric strength training (ST) are related to changes in intracortical excitability measured by magnetic brain stimulation (TMS) in the trained and the contralateral untrained biceps brachii (BB) and whether such changes scale with training intensity. On three separate days, 15 healthy young men performed one ST session of 12 sets of eight isometric contractions of the right elbow flexors at 0% (control session), 25%, or 75% of the maximal voluntary contraction (MVC) in a random order. Before and after each session separated at least by 1 week, motor evoked potential (MEP) amplitude, short‐interval intracortical inhibition (SICI), contralateral silent period (SP), and intracortical facilitation (ICF) generated by TMS were measured in the trained and the untrained BBs. Compared with baseline, MEPs recorded from the trained BB increased by ~47% after training at 75% of MVC (P < .05) but not after training at 0% (~4%) or 25% MVC (~5%, both P > .05). MEPs in the untrained BB and SICI, SP, and ICF in either BB did not change. Therefore, acute high‐intensity but not low‐intensity unilateral isometric ST increases CSE in the trained BB without modifications in intracortical inhibition or facilitation. Thus, increases in corticospinal neurons or α‐α‐motoneuron excitability could underlie the increases in CSE. Regardless of contraction intensity, acute isometric ST did not modify the excitability of the ipsilateral primary motor cortex measured by TMS.

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Section: Discussionmentioning

confidence: 95%

Section: Trained Sidementioning

confidence: 99%

Training intensity‐dependent increases in corticospinal but not intracortical excitability after acute strength training

Colomer‐Poveda

Hortobágyi

Keller

et al. 2019

Scandinavian Med Sci Sports

View full text Add to dashboard Cite

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“…With regard to the motor performance improvements, it is well known that the interplay between agonist and antagonist muscle activities, in a system composed of several muscles, bone segments and joints, take on a determinant role from both the biomechanical and motor task efficiency point of view [ 61 ]. Such improved centrally managed joint efficiency might also be a direct reason for the decreased fatigue.…”

Section: Discussionmentioning

confidence: 99%

“…FVT likely involves spindle afferents and it is known that their influence on motoneuron behavior, that is, both by favoring the recruitment [9] and by modulating the strength output decline [74]. Muscle strength enhancements, in sportive training, are improved by changes in alpha-motoneuron discharge [60,61]. Finally, the space perception results should be modified after FVT, this being potentially relevant for the balance improvements [75,76].…”

Section: Suggested Physiological Mechanismsmentioning

confidence: 99%

Is the Focal Muscle Vibration an Effective Motor Conditioning Intervention? A Systematic Review

Fattorini

Rodio

Pettorossi

et al. 2021

JFMK

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Mechanical vibration, applied to single or few muscles, can be a selective stimulus for muscle spindles, able to modify neuromuscular management, inducing short and long-term effects, are now mainly employed in clinic studies. Several studies reported as treatments with focal vibratory (FVT) can influence neuromuscular parameters also in healthy people. However, the application modalities and the consequent effects are remarkably fragmented. This paper aims to review these studies and to characterize the FVT effectiveness on long-term conditional capacities in relation to FVT characteristics. A systematic search of studies published from 1985 to 2020 in English on healthcare databases was performed. Articles had to meet the following criteria: (1) treatment based on a locally applied vibration on muscle belly or tendon; (2) healthy adults involved; (3) outcomes time analysis enduring for more than 24 h. Twelve studies were found, all of them presented an excellent quality score of ≥75%. All selected papers reported positive changes, comparable with traditional long-lasting training effects. Muscle force and power were the most investigated parameters. The after-effects persisted for up to several months. Among the different FV administration modalities, the most effective seems to show a stimulus frequency of ≈100 Hz, repeated more times within three-five days on a voluntary contracted muscle.

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“…Concurrently, in this study, SICI Mmax , MEP test and Mmax were tested in a more proximal muscular group (i.e., forearm muscle) than the above-cited study. This choice of testing FCR muscle was mainly motivated by the common use of wrist muscles in numerous strength-training programs that require pre-intervention and post-intervention SICI measurements [ 37 , 38 , 44 , 45 , 46 ]. The recruitment and discharge properties of motoneurones are known to be different between small hand muscles compared with more proximal arm muscles [ 47 ].…”

Section: Discussionmentioning

confidence: 99%

Influence of Voluntary Contraction Level, Test Stimulus Intensity and Normalization Procedures on the Evaluation of Short-Interval Intracortical Inhibition

et al. 2020

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Short-interval intracortical inhibition (SICI) represents an inhibitory phenomenon acting at the cortical level. However, SICI estimation is based on the amplitude of a motor-evoked potential (MEP), which depends on the discharge of spinal motoneurones and the generation of compound muscle action potential (M-wave). In this study, we underpin the importance of taking into account the proportion of spinal motoneurones that are activated or not when investigating the SICI of the right flexor carpi radialis (normalization with maximal M-wave (Mmax) and MEPtest, respectively), in 15 healthy subjects. We probed SICI changes according to various MEPtest amplitudes that were modulated actively (four levels of muscle contraction: rest, 10%, 20% and 30% of maximal voluntary contraction (MVC)) and passively (two intensities of test transcranial magnetic stimulation (TMS): 120 and 130% of motor thresholds). When normalized to MEPtest, SICI remained unchanged by stimulation intensity and only decreased at 30% of MVC when compared with rest. However, when normalized to Mmax, we provided the first evidence of a strong individual relationship between SICI and MEPtest, which was ultimately independent from experimental conditions (muscle states and TMS intensities). Under similar experimental conditions, it is thus possible to predict SICI individually from a specific level of corticospinal excitability in healthy subjects.

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Modulation of intracortical inhibition and excitation in agonist and antagonist muscles following acute strength training

Abstract: Modulation of intracortical inhibition and excitation in agonist and antagonist muscles following acute strength training.

Cited by 12 publications

References 69 publications

Training intensity‐dependent increases in corticospinal but not intracortical excitability after acute strength training

Training intensity‐dependent increases in corticospinal but not intracortical excitability after acute strength training

Is the Focal Muscle Vibration an Effective Motor Conditioning Intervention? A Systematic Review

Influence of Voluntary Contraction Level, Test Stimulus Intensity and Normalization Procedures on the Evaluation of Short-Interval Intracortical Inhibition

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