Modulation of host plant immunity by Tobamovirus proteins

Conti, Gabriela; Rodríguez, Marcelo; Venturuzzi, Andrea Laura; Asurmendi, Sebastián

doi:10.1093/aob/mcw216

Cited by 24 publications

(29 citation statements)

References 118 publications

(165 reference statements)

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“…Salicylic acid is involved in resistance to a broad spectrum of pathogens, and in particular viruses ( Alamillo et al. 2006 ; Conti et al. 2017 ).…”

Section: Resultsmentioning

confidence: 99%

Viral Fitness Correlates with the Magnitude and Direction of the Perturbation Induced in the Host’s Transcriptome: The Tobacco Etch Potyvirus—Tobacco Case Study

Cervera

Ambrós

Bernet

et al. 2018

Molecular Biology and Evolution

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Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their evolutionary potential. Darwinian fitness, defined as the advantage of a given genotype with respect to a reference one, is a complex property that captures, in a single figure, differences in performance at every stage of viral infection. To what extent does viral fitness result from specific molecular interactions with host factors and regulatory networks during infection? Can we identify host genes in functional classes whose expression depends on viral fitness? Here, we compared the transcriptomes of tobacco plants infected with seven genotypes of tobacco etch potyvirus that differ in fitness. We found that the larger the fitness differences among genotypes, the more dissimilar the transcriptomic profiles are. Consistently, two different mutations, one in the viral RNA polymerase and another in the viral suppressor of RNA silencing, resulted in significantly similar gene expression profiles. Moreover, we identified host genes whose expression showed a significant correlation, positive or negative, with the virus' fitness. Differentially expressed genes which were positively correlated with viral fitness activate hormone- and RNA silencing-mediated pathways of plant defense. In contrast, those that were negatively correlated with fitness affect metabolism, reducing growth, and development. Overall, these results reveal the high information content of viral fitness and suggest its potential use to predict differences in genomic profiles of infected hosts.

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“…Salicylic acid is involved in resistance to a broad spectrum of pathogens, and in particular viruses ( Alamillo et al. 2006 ; Conti et al. 2017 ).…”

Section: Resultsmentioning

confidence: 99%

Viral Fitness Correlates with the Magnitude and Direction of the Perturbation Induced in the Host’s Transcriptome: The Tobacco Etch Potyvirus—Tobacco Case Study

Cervera

Ambrós

Bernet

et al. 2018

Molecular Biology and Evolution

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“…This demonstrates that these hormones have a synergic effect on the resistance of melon plants against MNSV, which could play a prominent role in Hx-IR. Previous data have revealed that exogenous SA applications confer resistance against different viruses, although mechanisms are specific depending on both the host and the infecting virus ( Conti et al, 2017 ). In Nicotiana benthamiana plants, SA treatments lowered the coat protein levels of TMV and Potato virus X (PVX) during their compatible interactions ( Lee et al, 2011 ).…”

Section: Discussionmentioning

confidence: 99%

Hexanoic Acid Treatment Prevents Systemic MNSV Movement in Cucumis melo Plants by Priming Callose Deposition Correlating SA and OPDA Accumulation

et al. 2017

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Unlike fungal and bacterial diseases, no direct method is available to control viral diseases. The use of resistance-inducing compounds can be an alternative strategy for plant viruses. Here we studied the basal response of melon to Melon necrotic spot virus (MNSV) and demonstrated the efficacy of hexanoic acid (Hx) priming, which prevents the virus from systemically spreading. We analysed callose deposition and the hormonal profile and gene expression at the whole plant level. This allowed us to determine hormonal homeostasis in the melon roots, cotyledons, hypocotyls, stems and leaves involved in basal and hexanoic acid-induced resistance (Hx-IR) to MNSV. Our data indicate important roles of salicylic acid (SA), 12-oxo-phytodienoic acid (OPDA), jasmonic-isoleucine, and ferulic acid in both responses to MNSV. The hormonal and metabolites balance, depending on the time and location associated with basal and Hx-IR, demonstrated the reprogramming of plant metabolism in MNSV-inoculated plants. The treatment with both SA and OPDA prior to virus infection significantly reduced MNSV systemic movement by inducing callose deposition. This demonstrates their relevance in Hx-IR against MNSV and a high correlation with callose deposition. Our data also provide valuable evidence to unravel priming mechanisms by natural compounds.

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“…While TMV cucumber isolate showed that the 17 amino acid residues differ with tobacco isolate ( Table 3). The difference symptom expressions in indicator plants might be related to the differences in amino acids since the TMV CP gene is often responsible for differences in symptom development (Conti et al 2017). The importance of the viral CP in symptom development and in determining host range differences has been shown for tobamovirus-plant combinations (Luria et al 2017;Li et al 2017).…”

Section: Resultsmentioning

confidence: 99%

Characteristic of Tobacco mosaic virus isolated from cucumber and tobacco collected from East Java, Indonesia

et al. 2019

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Abstract. Listihani, Hidayat SH, Wiyono S, Damayanti TA. 2019. Characteristic of Tobacco mosaic virus isolated from cucumber and tobacco collected from East Java, Indonesia. Biodiversitas 20: 2937-2942. Tobacco mosaic virus (TMV) is a newly emerging virus infecting cucumbers in Java, Indonesia. The basic characters of the TMV isolated from cucumber need further study to investigate its differences with that from tobacco. Thus, the research aimed to study the character of both isolates based on their biological, symptomatology and nucleic acid of coat protein (CP) gene properties. The TMV isolates from both cucumber and tobacco were able to infect similar indicator plants with differing symptom expressions, especially on eggplant. Homology of nucleotide and amino acid of coat protein gene among isolates were about 90.3% and 91.0%, and homology to other isolates was about 87.6 to 93.8% and 89.3 to 96.8%, respectively. There were 17 amino acid differences in the CP gene which is presumed to differentiate those two isolates. Phylogenetic analysis CP gene sequences compared with corresponding isolates in GenBank showed the two isolates separated in different clades. The cucumber isolate from Kediri is closely related to tomato isolate from China in clade I, while tobacco isolate from Jember closely related to tobacco isolate from China in clade IIindicating the existence of two differ TMV variants. It will increase the difficulty to manage TMV in the fields.

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Modulation of host plant immunity by Tobamovirus proteins

Cited by 24 publications

References 118 publications

Viral Fitness Correlates with the Magnitude and Direction of the Perturbation Induced in the Host’s Transcriptome: The Tobacco Etch Potyvirus—Tobacco Case Study

Viral Fitness Correlates with the Magnitude and Direction of the Perturbation Induced in the Host’s Transcriptome: The Tobacco Etch Potyvirus—Tobacco Case Study

Hexanoic Acid Treatment Prevents Systemic MNSV Movement in Cucumis melo Plants by Priming Callose Deposition Correlating SA and OPDA Accumulation

Characteristic of Tobacco mosaic virus isolated from cucumber and tobacco collected from East Java, Indonesia

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