Abstract:Diabetes mellitus is a metabolic disease that is caused either by the decrease of insulin secretion from pancreatic β cells or the insensitivity of target cells against insulin. High glucose levels (hyperglycemia condition) can trigger the formation of free radicals, the main cause of diabetes micro and macrovascular complications. The formation of free radicals and AGE (advanced glycation end-products) is assumed to became the key factor in the decline of granulocyte cell production as well as the disruption … Show more
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