Modulation of chromium trioxide induced genotoxicity by methanol extract of leaves of &amp;lt;i&amp;gt;Trigonella foenum-graecum&amp;lt;/i&amp;gt; L

Sharma, Arti B.; Kumar, Manish; Chandel, Madhu; Kaur, Satwinderjeet

doi:10.5455/jeim.261111.or.017

Cited by 3 publications

(1 citation statement)

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“…Studies have also been done in microbial systems to observe the antimutagenic effect of fenugreek. Aqueous extract of fenugreek seeds inhibited the mutagenic activity of the direct acting mutagens against Salmonella typhimurium [ 46 ].…”

Section: Fenugreek As Potential Therapeutic Agent Against Several mentioning

confidence: 99%

Investigating Therapeutic Potential ofTrigonella foenum-graecumL. as Our Defense Mechanism against Several Human Diseases

Goyal

Gupta

Chatterjee

2016

Journal of Toxicology

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Current lifestyle, stress, and pollution have dramatically enhanced the progression of several diseases in human. Globally, scientists are looking for therapeutic agents that can either cure or delay the onset of diseases. Medicinal plants from time immemorial have been used frequently in therapeutics. Of many such plants, fenugreek is one of the oldest herbs which have been identified as an important medicinal plant by the researchers around the world. It is potentially beneficial in a number of diseases such as diabetes, hypercholesterolemia, and inflammation and probably in several kinds of cancers. It has industrial applications such as synthesis of steroidal hormones. Its medicinal properties and their role in clinical domain can be attributed to its chemical constituents. The 3 major chemical constituents which have been identified as responsible for principle health effects are galactomannan, 4-OH isoleucine, and steroidal saponin. Numerous experiments have been carried out in vivo and in vitro for beneficial effects of both the crude chemical and of its active constituent. Due to its role in health care, the functional food industry has referred to it as a potential nutraceutical. This paper is about various medicinal benefits of fenugreek and its potential application as therapeutic agent against several diseases.

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Section: Fenugreek As Potential Therapeutic Agent Against Several mentioning

confidence: 99%

Investigating Therapeutic Potential ofTrigonella foenum-graecumL. as Our Defense Mechanism against Several Human Diseases

Goyal

Gupta

Chatterjee

2016

Journal of Toxicology

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Chromium speciation, bioavailability, uptake, toxicity and detoxification in soil-plant system: A review

et al. 2017

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Biological Toxicity of Heavy Metal(loid)s in Natural Environments: From Microbes to Humans

Ding

Chen

Zhu

et al. 2022

Front. Environ. Sci.

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Excessive levels of heavy metal(loid)s (HMs) in natural environments pose a serious threat to living beings worldwide. HM exposure causes irreversible damage to structural components and metabolic processes in living organisms, as has been observed in multiple studies on various organisms. In the natural environment, biological individuals interact with others through the food web rather than exist independently, which facilitates the transfer of HMs in the food web. However, the difference in HM toxicity among different biological species has not been elucidated. This review provides information on the speciation and migration of HMs in different environments to clarify the HM exposure routes of different biological species. The differences in the biotoxicity of HMs to different species, from microbes to humans, are emphasized. The relationship between HM toxicity and biological species is confirmed by the fact that HMs can be transferred and bioaccumulated along the food chain. Effective strategies for decreasing HMs emissions and removing HMs from the environment are briefly discussed. Finally, the limitations of the present study and future perspectives are discussed.

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Modulation of chromium trioxide induced genotoxicity by methanol extract of leaves of <i>Trigonella foenum-graecum</i> L

Cited by 3 publications

References 0 publications

Investigating Therapeutic Potential ofTrigonella foenum-graecumL. as Our Defense Mechanism against Several Human Diseases

Investigating Therapeutic Potential ofTrigonella foenum-graecumL. as Our Defense Mechanism against Several Human Diseases

Chromium speciation, bioavailability, uptake, toxicity and detoxification in soil-plant system: A review

Biological Toxicity of Heavy Metal(loid)s in Natural Environments: From Microbes to Humans

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