Modulation interference microscopy as a promising method for assessing the risk of metastasis in patients with breast cancer

Biopolymer Matrices Based on Chitosan and Fibroin: A Review Focused on Methods for Studying Surface Properties

“…Obtaining quantitative values of the morphology of living cytoobjects makes it possible to track their change in real-time by obtaining 2D and 3D images. Due to the high speed of measurements and the non-invasiveness of this method, it has taken one of the central positions in the study of the tolerance of cellular objects to the surface of biomedical devices [99,104,105].…”

“…Thus, today, such microscopic methods as atomic force microscopy (AFM), scanning electron microscopy (SEM) and fluorescence and confocal microscopy [106][107][108][109] are There are many strategies for effectively solving problems associated with the most accurate and reliable measurement of the thickness of a thin polymer coating [103]-a theoretical calculation or an empirical characteristic of the system on an opaque artifact on the surface or in the thickness of the film, providing a signal model representing the response of the instrument in the absence of a film. In [104], samples of chitosan films were studied with a phase-modulation laser interferometric microscope. A non-invasive assessment of the effect of the structure, composition and conditions of modification of the biopolymer composites on the viability, adhesive properties and functional activity of the living blood cells (neutrophils, lymphocytes and platelets) in vitro was carried out.…”