Modulation comparée de l’axe hypophyso-surrénalien par les androgènes testiculaires chez deux rongeurs sahariens Gerbillus tarabuli et Meriones libycus

Zatra, Yamina; Aknoun-Sail, Naouel; Kheddache, Arezki; Benmouloud, Abdelouafi; Exbrayat, Jean-Marie; Khammar, Farida; Amirat, Zaïna

doi:10.1016/j.ando.2018.06.333

Cited by 1 publication

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“…43 The effect of gonadectomy, which induces significant weight, histological, and hormonal changes in the adrenal gland, on the pituitary–adrenal axis during the breeding season has been studied. Testosterone withdrawal activates corticosteroidogenesis, induces adrenal cortex hypertrophy, greater androgen receptor positivity, increases plasma cholesterol, and decreases ACTH, 43 –45 suggesting negative modulation of testosterone on the pituitary-adrenal axis of G. tarabuli , by acting directly on the adrenal cortex and/or probably via the central pathway by modulating the hypothalamic-pituitary hormonal activity. Thus, testosterone may be involved, at least in part, in determining the annual variations in adrenocortical activity.…”

Section: Introductionmentioning

confidence: 99%

Advances in research on the biology of the desert rodent Gerbillus tarabuli: a review

et al. 2022

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Selection of the appropriate species and strain of laboratory animals are among the scientist’s major concerns. Tarabul’s gerbil ( Gerbillus tarabuli) is a small, seasonally breeding, desert rodent native to Africa. Despite its unique biological features, which make it an ideal model candidate for biomedical research, only a few reports have used it in research. Hence, the present review aims to provide more data about this species, covering all aspects of its biology, such as taxonomy, morphology, anatomy, ecology, wildlife biology, molecular biology, physiology, neurobiology, genetics, reproduction, development, evolutionary biology, and conservation biology, and covers current progress in exploration of G. tarabuli, discussing its valuable characteristics, which are widely useful for research in various fields. This review paper is destined for biologists, scientists, mammologists, zoologists, academics, and students.

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