Abstract:Neuromodulation lends flexibility to neural circuit operation. However, the general notion that different neuromodulators sculpt neural circuit output into distinct and characteristic patterns is complicated by interindividual variability. In addition, some neuromodulators converge onto the same signaling pathways, with similar effects on neurons and synapses. We compared the effects of three neuropeptides on the rhythmic pyloric circuit in the crab Cancer borealis stomatogastric nervous system. Proctolin (PRO… Show more
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