Modulated light-activated electrochemistry at silicon functionalized with metal-organic frameworks towards addressable DNA chips

Wang, Jian; Yang, Zhao; Chen, Wei; Du, Liping; Jiao, Bo; Krause, Steffi; Wang, Ping; Wei, Qiuping; Zhang, Dewen; Wu, Chunsheng

doi:10.1016/j.bios.2019.111750

Cited by 19 publications

(14 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fundamental and applied research on the self-assembly of organic molecules on electrode surfaces continues to be an area of intense research. To date, the focus has been on the formation of self-assembled monolayers (SAMs) on gold electrodes using thiol or disulfide-terminated molecules, − but there is increasing interest of forming monolayers on a range of other electrodes. − The study by Chidsey and co-workers on Si–C-bound monolayers has helped to expand this research from metals to semiconductors. − In particular, monolayers on oxide-free silicon (Si–H) have gained significant interest because they enable combining the traditional semiconducting properties of Si with those of functional organic molecules. ,− For example, Si-based SAMs have been exploited in solar cell research, − biosensors, − fundamental electron transfer studies, − and molecular electronics. − …”

Section: Introductionmentioning

confidence: 99%

Nanoscale Silicon Oxide Reduces Electron Transfer Kinetics of Surface-Bound Ferrocene Monolayers on Silicon

Dief

Lyu

et al. 2021

J. Phys. Chem. C

View full text Add to dashboard Cite

Functionalizing Si with self-assembled monolayers (SAMs) paves the way for integrating the semiconducting properties of Si with the diverse properties of organic molecules. Highly packed SAMs such as those formed from alkyl chains protect Si from reoxidation in an ambient environment. Such monolayers have been largely considered oxide-free, but the effect of nanoscale reoxidation on the electrochemical kinetics of Si-based SAMs remains unknown. Here, we systematically study the effect of the oxide growth on the electrochemical charge-transfer kinetics of ferrocene-terminated SAMs on Si by exposing the surfaces to ambient conditions for controlled periods of time. X-ray photoelectron spectroscopy and atomic force microscopy revealed a gradual growth of silicon oxide (SiO x ) on the surfaces over time. The oxide growth is accompanied by a decrease in the ferrocene surface coverage and a concomitant decrease in the electron transfer rate constant (k et) measured by electrochemical impedance spectroscopy. The drop in k et is attributed to a greater spacing between the ferrocene moieties induced by the surface oxide, which in turn blocks lateral electron transfer between neighboring ferrocene moieties. These findings explain the highly scattered literature data on electron transfer kinetics for monolayers on Si and have implications for the proper design of Si-based molecular electronic devices.

show abstract

Section: Introductionmentioning

confidence: 99%

Nanoscale Silicon Oxide Reduces Electron Transfer Kinetics of Surface-Bound Ferrocene Monolayers on Silicon

Dief

Lyu

et al. 2021

J. Phys. Chem. C

View full text Add to dashboard Cite

show abstract

“…Starting from the seminal work of Sagiv in 1980, fundamental and applied research on the self-assembly of organic molecules onto electrode surfaces has continued gaining momentum . While most of the research on self-assembly to date has focused on gold surfaces by exploiting alkanethiol chemistry, the 1990s reports by Chidsey and co-workers of Si–C-bound monolayers have helped expand this research from metals to semiconductors. − Silicon remains the technologically most relevant semiconducting material, − and silicon electrodes that are functionalized with organic monolayers have broad application prospects in the fields of microscopy, , sensing, − chemical catalysis, (bio)molecular electronics, ,, and information storage. ,, …”

Section: Introductionmentioning

confidence: 99%

Absence of a Relationship between Surface Conductivity and Electrochemical Rates: Redox-Active Monolayers on Si(211), Si(111), and Si(110)

et al. 2021

View full text Add to dashboard Cite

Optimizing the kinetics of an electrode reaction is central to the design of devices whose function spans from sensing to energy conversion. Electrode kinetics depends strongly on electrode surface properties, but the search for optimal materials is often a trial-and-error process. Recent research has revealed a pronounced facet-dependent electrical conductivity for silicon, implicitly suggesting that rarely used crystallographic cuts of this technologically relevant material had been entirely overlooked for the fabrication of electrodes. By first protecting silicon from anodic decomposition through Si−C-bound organic monolayers, conductive atomic force microscopy demonstrates that conductivity decreases in the order (211) ≫ (110) > ( 111). However, charge-transfer rates for a model electrochemical reaction are similar on all these crystal orientations. These findings reveal the absence of a relationship between surface conductivity and kinetics of a surface-confined redox reaction and expand the range of silicon crystallographic orientations viable as electrode materials.

show abstract

“…Recently, light-addressable electrochemistry or light-activated electrochemistry (LAE), which can drive the Faradaic process in an amperometric fashion, has become another hot research spot in the construction of LAESs. , Based on an electrolyte–semiconductor (ES) structure, LAE allows light-induced local Faradaic currents to cross the electrode/electrolyte interface, which broadens the applications from potentiometric measurements to amperometric detection principles . For instance, LAE has been adopted for electrochemical analysis, − biomolecular sensing, , and live cell imaging. , The fundamental theory, spatial confinement and sensing performance of LAE, has been reviewed by Vogel et al It is noteworthy that another significant concept of photoelectrochemical (PEC) sensing possessing a working principle similar to LAE has also witnessed remarkable progress in the past two decades. − Most of this work benefited from the advantage of the high sensitivity of PEC due to the unique setup consisting of two separate energy forms, that is, using light as the excitation source and electricity as the detection signal. , The light addressability of PEC, however, has been rarely exploited and summarized.…”

mentioning

confidence: 99%

Light-Addressable Electrochemical Sensors toward Spatially Resolved Biosensing and Imaging Applications

Meng

Chen

et al. 2022

ACS Sens.

Self Cite

View full text Add to dashboard Cite

The light-addressable electrochemical sensor (LAES) is a recently emerged bioanalysis technique combining electrochemistry with the photoelectric effect in a semiconductor. In an LAES, a semiconductor substrate is illuminated locally to generate charge carriers in a well-defined area, thereby confining the electrochemical process to a target site. Benefiting from the unique light addressability, an LAES can not only detect multiple analytes in parallel within a single sensor plate but also act as a bio(chemical) imaging sensor to visualize the two-dimensional distribution of specific analytes. An LAES usually has three working modes: a potentiometric mode using light-addressable potentiometric sensors (LAPS) and an impedance mode using scanning photoinduced impedance microscopy (SPIM), while an amperometric mode refers to light-addressable electrochemistry (LAE) and photoelectrochemical (PEC) sensing. In this review, we describe the detection principles of each mode of LAESs and the concept of light addressability. In addition, we highlight the recent progress and advance of LAESs in spatial resolution, sensor system design, multiplexed detection, and bio(chemical) imaging applications. An outlook on current research challenges and future prospects is also presented.

show abstract

Modulated light-activated electrochemistry at silicon functionalized with metal-organic frameworks towards addressable DNA chips

Cited by 19 publications

References 36 publications

Nanoscale Silicon Oxide Reduces Electron Transfer Kinetics of Surface-Bound Ferrocene Monolayers on Silicon

Nanoscale Silicon Oxide Reduces Electron Transfer Kinetics of Surface-Bound Ferrocene Monolayers on Silicon

Absence of a Relationship between Surface Conductivity and Electrochemical Rates: Redox-Active Monolayers on Si(211), Si(111), and Si(110)

Light-Addressable Electrochemical Sensors toward Spatially Resolved Biosensing and Imaging Applications

Contact Info

Product

Resources

About