Modular Microstructured Reactors for Pilot‐ and Production Scale Chemistry

Abstract

In recent years, two strategies in continuous‐flow plant technology attracted strengthened interest: First, the use of microstructured devices as a new tool for process intensification and second, the modularity of interchangeable devices which leads to more flexibility. To take advantage of both, these approaches were combined within the EU‐project CoPIRIDE. Microstructured modular reactors were fabricated by novel manufacturing techniques. Different types of such reactors were characterized in terms of reaction engineering. Residence time distribution, heat transfer performance, pressure drop, and liquid‐liquid mixing performance were investigated.

Modular Process Engineering: Development of Apparatuses for Transformable Production Systems

“…The Coflore® Flow Reactor from AM Technology is an easy‐to‐scale reactor in continuous operation . The micro applications of Fraunhofer ICT‐IMM are also used in pilot and production plants and are intended to increase the flexibility of the systems by their modular design , . Another example is the Advanced‐Flow™ reactor from Corning.…”

Acoustophoretic focusing effects on particle synthesis and clogging in microreactors

“…Reactors with structured elements on the micro- and milli-scale are increasingly used for the continuous manufacturing of chemicals and pharmaceuticals,1–4 due to their advantages like large specific surface area, enhanced heat/mass transfer, intrinsic safety and fast scale-up 5–7. Despite these advantages, one major drawback greatly limiting their application is their susceptibility to channel clogging for flows containing solid particles 8–10.…”

Cover Picture: Modulable and Highly Diastereoselective Carbometalations of Cyclopropenes (Chem. Eur. J. 4/2014)

“…In recent decades, microdevices, also called micromixers or microreactors, have been widely studied and demonstrated to have remarkable potential for mixing processes 6–11. Numerous characterization techniques for the mixing performance of microdevices have emerged, both qualitative and quantitative ones 12–15.…”