Modifying effect of Siraitia grosvenori extract on piperonyl butoxide-promoted hepatocarcinogenesis in rats

Abstract

Siraitia grosvenori N S

Spontaneous Vesicle Formation from Sodium Salt of Acidic Sophorolipid and Its Application as a Skin Penetration Enhancer

“…The sweetening components in this plant include mogroside V and 11-oxo-mogroside V; tetraglucose conjugated mogrosides include mogroside IV and siamenoside I, and triglucose conjugated mogrosides include mogroside III. Previous studies on the pharmacological activities of SG extracts revealed anti-atherosclerotic effects 24 , anti-cancer activity 25,26 , anti-allergy activity 27 , and anti-diabetic effects 28,29 in animal models. Thus, they are of growing commercial interests in cosmetic industry.…”

Hyperproduction of β-Glucanase Exg1 Promotes the Bioconversion of Mogrosides in Saccharomyces cerevisiae Mutants Defective in Mannoprotein Deposition

“…Mogrosides (MGs) from the extracts of Siraitia grosvenorii Swingle fruits, also called monk fruit or Luo Han Guo (LHK), are a mixture of curcurbitane-type triterpene saponins . Several studies have reported the various biological functions of MG extracts, which include anti-inflammatory and antioxidation activities, insulin secretion stimulating effects, and antihepatitis virus activity. − Suzuki et al also demonstrated that mogroside III E (MG III E), a minor form of natural MGs with three glucose molecules attached to the C-3 and C-24 positions, exhibits the highest rat intestinal maltase inhibition activity among various MGs, including mogroside V (MG V), mogroside IV (MG IV), and siamenoside I (S I) . However, further studies of MG III E have been hindered by the lack of efficient techniques for obtaining sufficiently large quantities of pure compounds, which is a considerable problem as several types of glycosylated forms of MGs exist in natural extracts.…”