Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors (OASIS)

Miller, Michael E.; Rejeski, W. Jack; Messier, Stephen P.; Loeser, Richard F.

doi:10.1002/1529-0131(200108)45:4<331::aid-art345>3.0.co;2-6

Cited by 102 publications

(87 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If studies of the same cohort presented different information, reported on different prognostic factors (28,29), or presented results after different followup periods (30,31), both studies were included. In total, 18 studies were included in this review (27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44). A list of excluded studies is presented in Appendix 1 on the NIVEL Web site (available at: http://www.nivel.nl/systeem/scripts/downloadtracker.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Dijk

Dekker

Veenhof

et al. 2006

Arthritis & Rheumatism

220

149

View full text Add to dashboard Cite

Objective. To systematically review studies describing the course of functioning in patients with osteoarthritis (OA) of the hip or knee and identifying potential prognostic factors. Methods. A systematic search was performed. Studies involving patients with hip or knee OA, >6 months of followup, and outcome measures on functional status or pain were included. Methodologic quality was assessed using a standardized set of 11 criteria; a qualitative data analysis was performed.Results. Approximately 6,500 titles and abstracts were screened and 48 publications were considered for inclusion. Eighteen studies, 4 of which met the high methodologic quality criteria, were included. For hip OA, there was limited evidence that functional status and pain do not change during the first 3 years of followup. After 3 years, however, a worsening of functional status and pain was seen. For knee OA, there was conflicting evidence for the first 3 years and limited evidence for worsening of pain and functional status after 3 years. Furthermore, limited evidence was established for negative associations between future functional status and laxity, proprioceptive inaccuracy, age, body mass index, and knee pain intensity. In contrast, greater muscle strength, better mental health, better self-efficacy, social support, and more aerobic exercise were protective factors in the first 3 years. Conclusion. Pain and functional status in hip or knee OA seem to deteriorate slowly, with limited evidence for worsening after 3 years of followup. In specific subgroups, prognosis in the first 3 years of followup was either worse or better, as both risk factors and protective factors were identified. Prognostic factors included biomechanical factors, psychological factors, clinical factors, and treatment modalities. To strengthen the evidence, further high-quality longitudinal research on hip or knee OA functioning is needed.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Radiologic criteria (27)(28)(29)(30)34,38,39,43,44) or a combination of radiologic criteria and clinical symptoms (31)(32)(33)(35)(36)(37)40,42) were used in most of the studies. One study included patients diagnosed on the basis of American College of Rheumatology criteria (41,45,46).…”

Section: Functional Status and Pain In Hip And Knee Oamentioning

confidence: 99%

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Dijk

Dekker

Veenhof

et al. 2006

Arthritis & Rheumatism

220

149

View full text Add to dashboard Cite

show abstract

“…A downward spiral of pain, worse self-reported knee instability, muscle weakness, greater varus-valgus joint motion, and worse knee confidence may further exacerbate decreased activity, additionally increasing pain and reducing muscle strength. In support of this notion, patients with OA-related knee pain demonstrate reduced muscle strength compared to controls without knee pain (28), and both muscle strength and pain (29), strength and dynamic varus-valgus joint motion (12), as well as strength and self-efficacy (24), have been shown to interact when evaluating the effects on physical function.…”

Section: Discussionmentioning

confidence: 99%

Association of Knee Confidence With Pain, Knee Instability, Muscle Strength, and Dynamic Varus–Valgus Joint Motion in Knee Osteoarthritis

Skou

Wrigley

Metcalf

et al. 2014

Arthritis Care & Research

View full text Add to dashboard Cite

Objective. To investigate associations between self-reported knee confidence and pain, self-reported knee instability, muscle strength, and dynamic varus-valgus joint motion during walking. Methods. We performed a cross-sectional analysis of baseline data from 100 participants with symptomatic and radiographic medial tibiofemoral compartment osteoarthritis (OA) and varus malalignment recruited for a randomized controlled trial. The extent of knee confidence, assessed using a 5-point Likert scale item from the Knee Injury and Osteoarthritis Outcome Score, was set as the dependent variable in univariable and multivariable ordinal regression, with pain during walking, self-reported knee instability, quadriceps strength, and dynamic varus-valgus joint motion during walking as independent variables. Results. One percent of the participants were not troubled with lack of knee confidence, 17% were mildly troubled, 50% were moderately troubled, 26% were severely troubled, and 6% were extremely troubled. Significant associations were found between worse knee confidence and higher pain intensity, worse self-reported knee instability, lower quadriceps strength, and greater dynamic varus-valgus joint motion. The multivariable model consisting of the same variables significantly accounted for 24% of the variance in knee confidence (P < 0.001). Conclusion. Worse knee confidence is associated with higher pain, worse self-reported knee instability, lower quadriceps muscle strength, and greater dynamic varus-valgus joint motion during walking. Since previous research has shown that worse knee confidence is predictive of functional decline in knee OA, addressing lack of knee confidence by treating these modifiable impairments could represent a new therapeutic target.

show abstract

“…These results may therefore suggest that self-reported knee pain, stiffness, and dysfunction mediate the relationship between OA and poor muscle strength. This conclusion is supported by a cross-sectional analysis of more than 500 men and women with a mean age of approximately 55 years, which demonstrated that significant associations of hand ROA with grip strength and function were mediated by pain (26), and the Observational Arthritis Study in Seniors study also identified that knee pain intensity mediated the association between knee ROA and change in performance over 30 months (27). It is worth noting that in the present study, women with knee pain were no more likely than those without knee pain to have knee ROA, suggesting that other causes of joint pain may contribute to muscle declines.…”

Section: Discussionmentioning

confidence: 99%

Prospective study of self‐reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community‐dwelling older adults

Scott¹,

Blizzard²,

Fell³

et al. 2011

Arthritis Care & Research

112

View full text Add to dashboard Cite

Objective. To examine the potential role of self-reported joint pain, stiffness, and dysfunction, and radiographic osteoarthritis (ROA), in sarcopenia progression and falls risk in older adults. Methods. Seven hundred nine older adults (50% women, mean ؎ SD age 62 ؎ 7 years) were examined at baseline and followup (mean ؎ SD 2.6 ؎ 0.4 years). ROA was assessed using the Altman atlas, and pain at 7 anatomic sites was self-reported. Dual x-ray absorptiometry assessed leg lean mass, dynamometry assessed knee extension and whole leg strength, leg muscle quality (LMQ) was calculated as whole leg strength relative to leg lean mass, and the Physiological Profile Assessment assessed falls risk. Results. In women only, baseline knee pain predicted a greater decline in knee extension strength, whole leg strength, and LMQ, and a greater increase in falls risk. Severe knee pain, stiffness, and dysfunction predicted greater declines in knee extension strength and increases in falls risk (all P < 0.05). Hip pain also predicted a greater decline in knee extension strength (؊1.53 kg; 95% confidence interval [95% CI] ؊2.95, ؊0.11). No associations were observed between pain and sarcopenia indicators in men. Somewhat surprisingly, higher baseline total knee ROA score predicted a greater increase in mean leg lean mass (0.05 kg; 95% CI 0.02, 0.08) in both sexes. A path analysis demonstrated that knee ROA may contribute to declines in LMQ in women, through increases in pain, stiffness, and dysfunction. Conclusion. Knee and hip pain may directly contribute to the progression of sarcopenia and increased falls risk in older women.

show abstract

Modifiers of change in physical functioning in older adults with knee pain: the Observational Arthritis Study in Seniors (OASIS)

Cited by 102 publications

References 29 publications

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Association of Knee Confidence With Pain, Knee Instability, Muscle Strength, and Dynamic Varus–Valgus Joint Motion in Knee Osteoarthritis

Prospective study of self‐reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community‐dwelling older adults

Contact Info

Product

Resources

About