Modified Zinc Analysis Method and Serum and Urinary Zinc Levels in Control Subjects

Helwig, H.; Hoffer, Emanual M.; Thielen, William C.; Alcocer, A.; Hotelling, David R.; Rogers, William H.

doi:10.1093/ajcp/45.2.160

Cited by 17 publications

(6 citation statements)

References 9 publications

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“…15-17) and close to the amounts found in patients with hypertension, arthritis, and obesity, where it ranged from 470 to 550 µg day -1 . 17 Regarding zinc loss in urine, the values found in this study are within the range described by Schroeder and Nason, 18 in 1971, and above the output found by Helwig et al, 19 in 1966. However, a recent study in 2011 reported lower urinary iron excretion than the present values for all age ranges.…”

Section: Discussionsupporting

confidence: 85%

Impact of Aging on Urinary Excretion of Iron and Zinc

Pfrimer

Micheletto

Marchini

et al. 2014

Nutr Metab Insights

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PROJECTData about the influence of aging on urinary excretion of iron and zinc are scarce. The objective of the present study was to compare the concentration of zinc and iron in the urine of healthy elderly subjects and younger adults.PROCEDURESeven healthy elderly subjects and seven younger adults were selected and submitted to biochemical, clinical, and nutritional tests. After a fasting period, 12-hour urine was collected for the determination of iron and zinc concentrations by graphite furnace atomic absorption spectrophotometry.RESULTSUrinary zinc and iron concentrations of the elderly subjects were not significantly different from that of younger adults. However, the total zinc and iron urinary clearance in 24 hours for the elderly was significantly higher compared with that of younger adults.CONCLUSIONThere is an increase in urinary iron and zinc clearance with aging. The values reported in this manuscript may be used as references in future studies.

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Section: Discussionsupporting

confidence: 85%

Impact of Aging on Urinary Excretion of Iron and Zinc

Pfrimer

Micheletto

Marchini

et al. 2014

Nutr Metab Insights

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“…It was a little higher than the average normal daily urinary zinc excretion of 0 3 mg.Zn per day found by McCance and Widdowson (1942), and lower than the mean normal values given by other investigators (Helwig et al, 1966). It was also lower than the mean value reported by Prasad et al (1963b) in normal Egyptians.…”

Section: Discussioncontrasting

confidence: 57%

“…was significantly less than the mean plasma or serum zinc concentration for normal subjects found by other investigators (Berfenstam, 1952;Helwig et al, 1966). Plasma and serum zinc levels have been found to be the same for the same subject (Berfenstam, 1952).…”

Section: Discussionmentioning

confidence: 55%

“…Zinc analysis A modified zinc analysis technique, based essentially on the methods of Helwig, Hoffer, Thielen, Alcocer, Hotelling, and Rogers (1966) and Malmstrom (1956), was used. Precautions to avoid contamination were taken as outlined by Malmstrom.…”

Section: Methodsmentioning

confidence: 99%

“…zinc) was wet-ashed (Helwig et al, 1966). The tartrate solution was added to the acid-digested sample, which was then titrated with ammonia to a blue colour, a drop of bromocresol solution acting as indicator.…”

Section: Methodsmentioning

confidence: 99%

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Chronic exposure to zinc of furnace operators in a brass foundry

Hamdi

1969

Occupational and Environmental Medicine

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). Brit. J. industr. Med., 26,[126][127][128][129][130][131][132][133][134]. Chronic exposure to zinc of furnace operators in a brass foundry. Twelve furnace operators with chronic exposure to zinc oxide fumes in a brass foundry and 10 normal non-exposed control subjects were studied. Simultaneous determinations of zinc concentrations in the plasma, blood corpuscles, whole blood, and urine were made for each worker and control subject, and in the basal fasting gastric juice and in the gastric secretion half an hour and one hour after gastric stimulation by alcohol in eight workers and seven control subjects.The workers showed a statistically significant increase of zinc concentration in the blood corpuscles, whole blood, and basal fasting gastric juice compared with the control subjects. Urinary zinc excretion was slightly increased in the exposed workers. The increase in the plasma zinc in the workers was not statistically significant.Stomach aspiration after alcohol showed a depression of the mean zinc concentration in the gastric secretion after half an hour with a subsequent increase to approximately the fasting level after one hour in both the normal subjects and the workers. Mean zinc concentrations in the gastric juice half an hour and one hour after stomach stimulation were higher in the workers, but the increase was not statistically significant.It is suggested that the zinc absorbed by these workers is rapidly eliminated from the plasma to be excreted through the gastro-intestinal and urinary tracts; excess zinc is stored in the blood corpuscles. The increased zinc concentration in the gastric secretion of these workers might account, in part, for the high incidence of gastric complaints among them.

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Serum zinc and copper in myocardial infarction with particular reference to prognosis

Jain

Mohan

1991

Biol Trace Elem Res

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Serum copper and zinc estimations in humans were made to find their diagnostic and prognostic value in cases of myocardial infarction. Following infarction, there was an increase in serum copper levels from the first 24 h up to the 7th day, with gradual decline that did not reach the normal value up to the 14th day. The serum zinc levels declined in the first 24 h until the 4th day and increased to the normal value on the 14th day. It is concluded that, for diagnosis of myocardial infarction, serum zinc levels are more useful during the first week and copper levels in the second week after the onset of infarction.

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Modified Zinc Analysis Method and Serum and Urinary Zinc Levels in Control Subjects

Cited by 17 publications

References 9 publications

Impact of Aging on Urinary Excretion of Iron and Zinc

Impact of Aging on Urinary Excretion of Iron and Zinc

Chronic exposure to zinc of furnace operators in a brass foundry

Serum zinc and copper in myocardial infarction with particular reference to prognosis

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