containing polyetherguanidinium iodides showed the highest activity against such microscopic fungi as Cladosporium cladosporioides, Acremonium strictum, Alternaria alternate, Cladosporium sphaerospermum, Paecilomyces variotii, Stachybotrys chartarum. Also noteworthy is the selective effect of the obtained polymers on individual isolates. Conclusions. The obtained polyetherguanidinium iodides of different molecular weight at a concentration of 1-3% showed bactericidal activity against Staphylococcus aureus 451, Escherichia coli 475, Klebsiella pneumoniae 479 and fungicidal effect against all fungi studied by us and can be used as disinfectants for indoor treatment.