Modified technique of suction blistering for epidermal grafting in vitiligo

Gupta, Somesh; Shroff, Satish; Gupta, Sanjeev

doi:10.1046/j.1365-4362.1999.00702.x

Cited by 91 publications

(91 citation statements)

References 16 publications

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“…45 Additionally, BG has a repigmentation rate ranging from 80 to 90%. 14,16,17 PG is no longer recommended as it has the highest rate of adverse effects and poor cosmetic results. The suction blister procedure is an alternative, but is less effective than STSG, being time-consuming and suited to the treatment of small areas.…”

Section: Discussionmentioning

confidence: 99%

“…Grafts, harvested by cutting the roof of the blisters, are grafted onto the recipient site, which has been prepared by dermabrasion, 13 laser abrasion, 14 producing blisters induced by suction, 15 liquid nitrogen 7 or psoralen plus ultraviolet A. 16 Various types of suction apparatus are used to produce blisters depending upon the preference of the operating surgeon. [15][16][17][18] The reported time for suction blister development varies between 1Á5 and 3 h. 13 Gupta and Kumar 19 reported a case series of 10 adolescents aged between 11 and 19 years who had SV or residual patches of generalized vitiligo.…”

mentioning

confidence: 99%

“…16 Various types of suction apparatus are used to produce blisters depending upon the preference of the operating surgeon. [15][16][17][18] The reported time for suction blister development varies between 1Á5 and 3 h. 13 Gupta and Kumar 19 reported a case series of 10 adolescents aged between 11 and 19 years who had SV or residual patches of generalized vitiligo. They found that 13 of the 15 patches in eight of the 10 patients showed > 75% repigmentation.…”

mentioning

confidence: 99%

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Surgical interventions for vitiligo: an evidence-based review

Mulekar¹,

Isedeh

2013

Br J Dermatol

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SummaryBackground Vitiligo is a disfiguring disease, characterized frequently by the presence of de-pigmented macules and/or patches. Traditional therapies are essentially medical and are most preferred by dermatologists. Surgical therapies, however, are amongst the most effective interventions for vitiligo but are limited by their invasive nature, as well as the training and expertise needed to perform specific procedures. Objectives To assess the evidence for the effectiveness, safety and applicability of the various surgical methods in the treatment of vitiligo. Methods For this systematic review of vitiligo surgical therapies, our searches included: PubMed, MEDLINE and Cochrane databases. Results We reviewed research studies reporting on split thickness skin grafts (STSG), punch/mini-graft, blister roof grafting, cultured and non-cultured cellular transplantation (MKTP). While all methods vary in their repigmentation outcomes, STSG is found to have the highest repigmentation success rate. Overall, post-operative complications included milia, scarring, cobblestone appearance or hyperpigmentation of treated areas. Conclusion This review highlights the need for more randomized controlled trials in this field, underpinned by a more standardized objective approach to the assessment of repigmentation following surgical interventions.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Surgical interventions for vitiligo: an evidence-based review

Mulekar¹,

Isedeh

2013

Br J Dermatol

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“…28 Gupta et al observed that the anterolateral thigh requires the least time (1.5 hours) for formation of a blister. 29 The mechanical split occurs at the dermoepidermal junction. In older individuals, weak adherence at dermoepidermal junction makes the separation easier and faster.…”

Section: Blister Graftingmentioning

confidence: 99%

“…10 Some techniques can reduce the time required for blister formation, such as an intradermal injection of normal saline, application of heat, increase of negative pressure by 100 mmHg when the small vesicles appear. 29 Lee and Jang reported that the preparation of donor sites with PUVA induces an increasing number of melanocytes, therefore improving the clinicalresults. 30 The recipient site is prepared by dermabrasion, ablation by erbium YAG laser and pulsed carbondioxide laser.…”

Section: Blister Graftingmentioning

confidence: 99%

Surgical management of vitiligo - An approach to the patient

Manchanda

Bansal

Pandey

2013

Nepal J Dermatol Venereol & Leprol

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Vitiligo vulgaris is an acquired chronic pigmentary disorder with an average world wide incidence of approximately 1%. Clinical classification of vitiligo is based on the distribution and extension of lesions as localized, generalized, and universal. As vitiligo has great psychosocial implications especially in dark-skinned individuals, treatment should begin early. Currrent modalities of treatment include medical therapy, surgical modalities and laser. Medical treatment options include topical corticosteroids, calcineurin inhibitors, vitamin-D derivatives, phototherapy (ultraviolet A [UVA], narrowband UVB), photochemotherapy (psoralen plus UVA [PUVA]. Surgical methods used in the management of vitiligo gave cosmetically acceptable results in short periods. Successful treatment with various surgical techniques requires an appropriate selection of patients mainly focusing upon the stability of the clinical disease. The choice of the procedure always depends upon the age, the area involved, site and the cosmetic need of the patient. The nature of the procedure, expected outcome and the complications should be discussed with the patient in detail. This article mainly deals with various dermatosurgical approaches in brief available till date for the treatment of vitiligo.

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