Modified Nissen Fundoplication for Late Dumping Syndrome After Roux-en-Y Gastric Bypass

Maurissen, J.; Yercovich, Nathalie; Aelst, P. Van; Dillemans, Bruno

doi:10.1007/s11695-021-05310-3

Cited by 5 publications

(3 citation statements)

References 9 publications

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“…76 Apart from a possible target of therapy as a delay in gastric pouch emptying, slowing the esophageal passage of food to the gastric pouch is also reported to be a target for intervention in dumping syndrome. 77 A case report on a modified Nissen fundoplication after RYGB -by creating a cuff around the esophageal-gastric junction with the fundus of the remnant stomach -showed clinical success in managing dumping syndrome symptoms in one female patient. As the follow-up was rather short, the occurrence of late complications after surgery, such as dysphagia, esophageal stasis or recurrent symptoms remains unclear.…”

Section: New Developments In Surgical and Endoscopic Interventionmentioning

confidence: 99%

“…As the follow-up was rather short, the occurrence of late complications after surgery, such as dysphagia, esophageal stasis or recurrent symptoms remains unclear. 77 Use of the above-mentioned experimental surgical and endoscopic techniques has resulted in impressive success rates in otherwise therapy-refractory patients. These techniques are currently certainly not ready for implementation in daily clinical practice.…”

Section: New Developments In Surgical and Endoscopic Interventionmentioning

confidence: 99%

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Dumping Syndrome: Pragmatic Treatment Options and Experimental Approaches for Improving Clinical Outcomes

Masclee,

Masclee

2023

CEG

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Dumping syndrome is a common complication after esophageal, gastric and bariatric surgery and has a significant negative impact on the quality of life of patients. This narrative review describes the clinical syndrome, pathophysiology, diagnosis and reports on standard and pragmatic therapeutical treatment options in order to improve the clinical outcome of patients with dumping syndrome. Dumping syndrome consists of early and late dumping symptoms and can be diagnosed using clinical parameters with the help of the Sigstad's score, questionnaires or by provocative testing. The prevalence of dumping syndrome varies depending on the employed definition of dumping syndrome. Overall, dumping syndrome is more frequent nowadays due to increasing numbers of upper gastrointestinal and bariatric surgeries being performed. First treatment step includes dietary adjustment and dietary supplements, which are often sufficient to manage symptoms for the majority of patients. Next step of therapy includes acarbose, which is effective for late dumping symptoms, but the use is limited due to side effects. Somatostatin analogues are indicated after these two steps have failed. Somatostatin analogues are very effective for controlling early and late dumping, also in the long term. Glucagon like peptide-1 receptor agonists, endoscopic and surgical (re)interventions are reported as treatment options for refractory dumping syndrome; however, their use is not recommended in clinical practice due to the limited evidence on and uncertainty of outcomes. These alternatives should be considered only as last resort options in patients with otherwise refractory and invalidating dumping syndrome.

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Section: New Developments In Surgical and Endoscopic Interventionmentioning

confidence: 99%

Section: New Developments In Surgical and Endoscopic Interventionmentioning

confidence: 99%

Dumping Syndrome: Pragmatic Treatment Options and Experimental Approaches for Improving Clinical Outcomes

Masclee,

Masclee

2023

CEG

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“…They opted to perform the same procedure to slow down the passage of food through the gastric pouch. This procedure can be performed as a revision procedure after Roux-en-Y gastric bypass for the treatment of postoperative dumping syndrome [11].…”

Section: Background and Rationale {6a}mentioning

confidence: 99%

A laparoscopic one anastomosis gastric bypass with wrapping versus nonwrapping fundus of the excluded part of the stomach to treat obese patients (FundoRingOAGB trial): study protocol for a randomized controlled trial

Ospanov

Yeleuov

Fursov

et al. 2022

Trials

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Background Laparoscopic one anastomosis gastric bypass (LOAGB) is a simple variation of gastric bypass and has gained worldwide popularity with clinical outcomes similar to laparoscopic Roux-en-Y gastric bypass (LRYGB) for weight loss and management of comorbidities. However, biliary reflux to the esophagus negates the benefits of LOAGB. In addition, weight gain after LOAGB and after LRYGB is a major problem in bariatric surgery. The aim of this article is to describe the design and protocol of a randomized controlled trial comparing the outcomes of two methods of LOAGB: experimental method with wrapping versus standard method nonwrapping fundus of the excluded part of the stomach to prevent weight regain and biliary reflux after LOAGB. Methods The study was designed as a single-center prospective, interventional, randomized controlled trial. Masking: None (open label). Allocation: randomized. Enrollment: 100 obese patients. The relevant ethics committee approved the trial protocol. The endpoints (body mass index, bile reflux in the esophagus, other reflux symptoms) will be assessed presurgery and postsurgery (12, 24, and 36 months postoperatively). Discussion With its 3-year follow-up time, this RCT will provide important data on the impact of wrapping the fundus of the excluded part of the stomach to prevent weight regain and biliary reflux after LOAGB. Trial registration ClinicalTrials.govNCT04834635. Registered on 8 April 2021.

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Laparoscopic Roux-en-Y Gastric Bypass: Current Controversies

Higa¹,

2022

Obesity, Bariatric and Metabolic Surgery

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Modified Nissen Fundoplication for Late Dumping Syndrome After Roux-en-Y Gastric Bypass

Cited by 5 publications

References 9 publications

Dumping Syndrome: Pragmatic Treatment Options and Experimental Approaches for Improving Clinical Outcomes

Dumping Syndrome: Pragmatic Treatment Options and Experimental Approaches for Improving Clinical Outcomes

A laparoscopic one anastomosis gastric bypass with wrapping versus nonwrapping fundus of the excluded part of the stomach to treat obese patients (FundoRingOAGB trial): study protocol for a randomized controlled trial

Laparoscopic Roux-en-Y Gastric Bypass: Current Controversies

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