Modified Fujiwara reaction for the determination of trichloroacetic acid

Fluorogenic Phenothiazine‐Derivative as Radical Sensors

“…Fujiwara reactions have generally been used for the detection of CHCs in solution. [24][25][26][27][28][29] This reaction is used for the spectroscopic detection of CHCl 3 , was first reported in 1916, and originally depended on a twophase system containing and NaOH aq layer and pyridine layer to CHCl 3 . [30] Then, this mixture was heated to obtain an intense red color that was monitored spectroscopically for chloroform identification and quantification.…”

“…There is a need to develop a direct, simple, and low‐cost method to detect chlorinated organic solvents, especially CHCl 3 , in the environment and residues in pharmaceutical products. Fujiwara reactions have generally been used for the detection of CHCs in solution [24–29] . This reaction is used for the spectroscopic detection of CHCl 3 , was first reported in 1916, and originally depended on a two‐phase system containing and NaOH aq layer and pyridine layer to CHCl 3 [30] .…”

Fast, Low cost, and facile phenothiazine radical based photoinduced sensors for rapid detection of chloroform and chlorinated solvents in liquid and gas phases†

“…Fujiwara reactions have been generally used for the detection of CHCs in solution. [24][25][26][27][28][29] This reaction is used for the spectroscopic detection of CHCl 3 , is firstly reported in 1916 and originally depends on a two-phase system containing and NaOH aq layer and pyridine layer to CHCl 3 . 30 Then, this mixture was heated to obtain an intense red colour that was monitored spectroscopically for chloroform identification and quantification.…”

Pyrrolo-[3,2-b]pyrroles for Photochromic Analysis of Halocarbons

“…For example, thermal decomposition of CHCl 3 releases harmful HCl fumes and phosgene vapor or emits dioxins from incineration . Therefore, monitoring the halocarbon contaminations, either qualitatively or quantitatively, is of great importance in the area of analytical chemistry. − This attracts a lot of scientists to work on instrumental analyses as well as sensor fabrications. − For example, Xue reported in 2015 significant progress in the design of optical sensors for the quantitative detection of trace chloroform in ethyl cellulose based on Fujiwara reactions. − Conversely, to carry out on-site monitoring of halocarbon contamination, a fast visualization detection method for halocarbons by the naked eyes is highly desired for qualitative screening. In this article, we will demonstrate fast detection based on our novel photochromic molecules.…”