Modified ESR‐based photosafety test (ESR‐PT) detecting singlet oxygen and free radical formation
Masumi Hinoshita,
Takayuki Abe,
Asako Sato
et al.
Abstract:The electron spin resonance‐based photosafety test (ESR‐PT) was modified using a new parameter, photoreactivity index (PRI), to detect singlet oxygen and free radical photoproducts simultaneously. With this modification, the modified ESR‐PT is expected to reduce the number of false negative results due to chemicals producing free radical photoproducts other than singlet oxygen. The assay performance of the modified ESR‐PT was evaluated using 56 chemicals, including hydrophobic chemicals. When using the PRI cut… Show more
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