Modified Constraint-Induced Movement Therapy Improves Fine and Gross Motor Performance of the Upper Limb in Parkinson Disease

Lee, Kyoung-Suk; Lee, Wanhee

doi:10.1097/phm.0b013e31820b15cd

Cited by 45 publications

(37 citation statements)

References 22 publications

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“…At last, 18 trials published between 1996 and 2013 were included in our meta-analysis [7]–[9], [14]–[28]. 17 literatures were eliminated for the reasons that 2 of them failed to randomize [29], [30], 8 without available data for the meta-analyses [31]–[38], and 7 violated the inclusion criteria [39]–[45]. Detailed selection process was showed in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Aerobic Exercise for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

et al. 2014

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BackgroundAlthough some trials assessed the effectiveness of aerobic exercise for Parkinson's disease (PD), the role of aerobic exercise in the management of PD remained controversial.ObjectiveThe purpose of this systematic review is to evaluate the evidence about whether aerobic exercise is effective for PD.MethodsSeven electronic databases, up to December 2013, were searched to identify relevant studies. Two reviewers independently extracted data and assessed methodological quality based on PEDro scale. Standardised mean difference (SMD) and 95% confidence intervals (CI) of random-effects model were calculated. And heterogeneity was assessed based on the I2 statistic.Results18 randomized controlled trials (RCTs) with 901 patients were eligible. The aggregated results suggested that aerobic exercise should show superior effects in improving motor actions (SMD, −0.57; 95% CI −0.94 to −0.19; p = 0.003), balance (SMD, 2.02; 95% CI 0.45 to 3.59; p = 0.01), and gait (SMD, 0.33; 95% CI 0.17 to 0.49; p<0.0001) in patients with PD, but not in quality of life (SMD, 0.11; 95% CI −0.23 to 0.46; p = 0.52). And there was no valid evidence on follow-up effects of aerobic exercise for PD.ConclusionAerobic exercise showed immediate beneficial effects in improving motor action, balance, and gait in patients with PD. However, given no evidence on follow-up effects, large-scale RCTs with long follow-up are warrant to confirm the current findings.

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Section: Resultsmentioning

confidence: 99%

Aerobic Exercise for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

et al. 2014

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“…Indeed, the training effect found on TG was enough to approach the patients' performance to healthy elderly on TUG (8.8 to 9.1 seconds [32]). Also, the reduction presented by our subjects were highly superior to that observed on both healthy elderly (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19).8% [32][33][34]). This data is particularly important, since improvement in mobility reduces the risk of falling and therefore, reduces patients' mortality and morbidity [35].…”

Section: Discussionmentioning

confidence: 56%

“…Many specific exercise programs have been suggested to reduce motor impairments of PD patients, such as walking exercises [15], resistance training [16], constrained-induced movement therapy [17], attention focused exercises [18], and others. The rationale of some of these programs is that patients do not present only the disease impairments, but also suffers the effects of the ageing physiological process.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Multimodal Exercise Program Enhances Mobility of Patients with Parkinson’s Disease

Pereira

Ferreira

Caetano

et al. 2012

ISRN Rehabilitation

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Objective. This study aimed to evaluate the effect of a long-period multimodal exercise program on balance, mobility and clinical status of patients with Parkinson's disease (PD). Methods. Thirty-three PD patients were assigned into two groups: a training group (TG-n = 22; aged 67.23 ± 8.39 years) and a control group (CG-n = 9; aged 71.56 ± 8.50 years). The TG patients were enrolled in a 6-month multimodal exercise program. This program was designed to improve physical capacity components and to reduce PD impairments. Balance and mobility were assessed immediately before and after the training protocol using the Berg Balance Scale (BBS), the "Timed up and go" (TUG), and the Posture Locomotion Test (PLM). Also, clinical variables were assessed (disease stage and impairments). Results. The TG showed an improvement in the TUG (P = 0.006) while CG were not influenced by the 6-months period. Both groups showed no differences for BBS and PLM and for their disease impairments-assessed through the Unified Parkinson's disease Scale. Conclusions. Long-term multimodal exercise programs are able to improve mobility of patients with Parkinson's disease and therefore should be used on clinical day life.

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“…The FM upper limb section allows a maximum score of 66, with sub-scores of 36 for the upper arm, 10 for the wrist, 14 for the hand, and 6 for coordination and speed of movement [16,17]. …”

Section: Methodsmentioning

confidence: 99%

Robot-assisted arm training in patients with Parkinson’s disease: a pilot study

Picelli

Tamburin

Passuello

et al. 2014

J NeuroEngineering Rehabil

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BackgroundDespite the growing diffusion of robotic devices in neurorehabilitation, no previous study investigated the effects of robotic training on arm impairment due to Parkinson’s disease. The aim of this pilot study was to evaluate whether robot-assisted arm training might improve upper limb function in patients with Parkinson’s disease.FindingsTen patients with Parkinson’s disease (Hoehn and Yahr stage 2.5-3) received ten, 45-minute, treatment sessions, five days a week, for two consecutive weeks. Robot-assisted arm training was performed with the Bi-Manu-Track (Reha-Stim, Berlin, Germany) that provides a computer-controlled, repetitive, bilateral, mirror-like practice of forearm pronation/supination and wrist extension/flexion. Patients were trained according to the following modalities: passive-passive (both arms moved by the machine) and active-active (both arms actively moving against resistance). The dominant upper limb was evaluated before and immediately after treatment as well as at two weeks of follow-up. Outcomes were the nine-hole peg test, the Fugl-Meyer assessment (upper limb section) and the Unified Parkinson’s Disease Rating Scale. After treatment, a significant improvement was found in the nine-hole peg test (P = 0.007) as well as in the upper limb section of the Fugl-Meyer assessment (P = 0.012). Findings were confirmed at the 2-week follow-up evaluation only for the nine-hole peg test (P = 0.007). No significant improvement was found in the Unified Parkinson’s Disease Rating Scale at both post-treatment and follow-up evaluations.ConclusionsOur findings support the hypothesis that robot-assisted arm training might be a promising tool in order to improve upper limb function in patients with Parkinson’s disease.

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Modified Constraint-Induced Movement Therapy Improves Fine and Gross Motor Performance of the Upper Limb in Parkinson Disease

Abstract: Modified constraint-induced movement therapy improves fine and gross motor performances of the upper limb in people with Parkinson disease. Therefore, the therapy would be recommended as an effective treatment for them.

Cited by 45 publications

References 22 publications

Aerobic Exercise for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Aerobic Exercise for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Long-Term Multimodal Exercise Program Enhances Mobility of Patients with Parkinson’s Disease

Robot-assisted arm training in patients with Parkinson’s disease: a pilot study

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