Modified biomimetic core–shell nanostructures enable long circulation and targeted delivery for cancer therapy

Abstract

Significant progress has been made in the application of nanoparticle drug carriers in the treatment of cancer. However, the clearance of nanoparticles by the reticuloendothelial system limits their circulation time...

Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy

“…MSNs with a large pore size were synthesized according to our previously reported approach. 33 As shown in Fig. 1a, the MSN has a distinctive dendritic pore structure.…”

Phosphazene Cyclomatrix Network-Based Polymer: Chemistry, Synthesis, and Applications

“… 81 − 83 Morphology-focused carriers with uniform hollow structures need an hour to efficiently run a drug delivery system, and these materials have the potential to deliver the guest molecules in systems with minimum damage to human body cells. 84 − 86 Until now, polyphosphazene microspheres have been utilized for modern day drug delivery systems because they can provide the monodispersion in solutions carrying large amounts of guest molecules of the drugs. 80 , 87 − 89 The biocompatibility and biodegrability of cyclopolyphosphazene materials are well-known, and many research groups 87 , 90 have used these molecules as biomaterials.…”

“…The cyclopolyphosphazenes have been used in biomedical applications and play a role in human health betterment via a drug delivery technique. , This drug delivery technique has many benefits over traditional and conventional types of drug dosage systems. , The drug delivery system reduced the toxicity, improved the efficiency in the context of target tissues, and improved the health condition of the patient. − Morphology-focused carriers with uniform hollow structures need an hour to efficiently run a drug delivery system, and these materials have the potential to deliver the guest molecules in systems with minimum damage to human body cells. − Until now, polyphosphazene microspheres have been utilized for modern day drug delivery systems because they can provide the monodispersion in solutions carrying large amounts of guest molecules of the drugs. ,− The biocompatibility and biodegrability of cyclopolyphosphazene materials are well-known, and many research groups , have used these molecules as biomaterials. Liu and co-worker synthesized the highly cross-linked, mesoporous, and most importantly hollow core submicrospheres and used them as drug delivery carriers .…”