Modification of the biocompatible and haemocompatible properties of polymer substrates by plasma-deposited fluorocarbon coatings

Improving blood compatibility of intravascular oxygen sensors via catalytic decomposition of S-nitrosothiols to generate nitric oxide in situ

“…At the same time, using the 3-m Cu 0 particles produces slightly rougher sensor surfaces than the controls (based on scanning electron micrographs (SEM), not shown here). This may put the NO-generating sensors at a disadvantage since rougher surfaces are prone to induce more thrombus formation [31]. However, it was found that much smoother surfaces can be readily achieved using the polymer films containing the Cu 0 nanoparticles as the catalytic layer, with negligible change of surface roughness as determined by SEM.…”

Surface Processing Using Cold Atmospheric Pressure Plasmas

“…They have applications in microelectronics, textiles, and anticorrosion coatings. Due to their chemical inertness and low surface energy, they have also been studied in biological applications and have been shown to exhibit nonthrombogenic properties, a resistance to platelet adhesion, activation, a resistance to protein adsorption, and blood compatibility (59,60). While a detailed study of blood compatibility of fluoropolymer films has not yet been carried out, it has been shown that the adsorption of fibrinogen, a protein present in blood and involved in the coagulation cascade, is related to the fluorine-carbon (F/C) ratio, surface morphology, and wettability (61).…”

The biocompatibility of self-assembled brush polymers bearing glycine derivatives

“…With the aim of improving the biocompatibility of biomaterials, surface modification with established materials has recently been extensively studied [2][3][4][5][6][7][8][9][10][11][12][13][14]. Self-assembled monolayer (SAM) interfaces have gained wide acceptance, so this surface modification method has experienced rapid progress.…”