Modification of styrene polymer by attaching suitable groups as side chain

Abstract

Chemical modification of inexpensive commercial polymers, such as styrene, is a safe methodology to obtain new copolymers. The 4-chloromethyl styrene (CMS) was copolymerized with styrene (in various mole ratios) by free radical polymerization method at 70 ºC using α,α-azobis(isobutyronitrile) (AIBN) as an initiator. The azide ion was covalently attached to the obtained copolymers with replacement of all the chlorine atoms in CMS units. The 1,3-dipolar click cycloaddition reaction between azido polymers and dimethyl acetylene dicarboxylate (DMAD) yielded polymers with 1,2,3-triazoles in side chain. The polymers, obtained in quantitative yields, were characterized by FT-IR and 1 H NMR spectroscopy; thermogravimetric analysis (TGA) and GPC studies. The thermogravimetric analysis (TGA) indicated that the thermal stability of copolymers increases with incorporation of 1,2,3-triazole groups in side chains of copolymers.

Novel Carriers for Oral Delivery of Hydrophobic Drugs

“…As shown in Scheme 3, GATA was deprotected using a catalytic quantity of sodium methoxide in methanol [13]. The FT-IR spectrum shows the complete Odeacetylation.…”

“…Cubane-1,4-bis (methacryloyloxyethyl) carboxylate (CA), glucose-6-acrylate-1,2, 3,4-tetraacetate (GATA) and glucose-6-acrylate (GA) were prepared using the methods described in the literature [11][12][13]. Estradiol was purchased from SigmaAldrich.…”

Synthesis and characterization of new nitrogen-rich polymers as candidates for energetic applications

“…Azaheterocycles are obviously suitable scaffolds for achieving nitrogen-rich polymers. There is a considerable interest in polyvinyltetrazoles (PVT) containing a large amount of nitrogen because of their powerful energetics, [1][2][3] interpolymer complexity, [4,5] biological activity, high thermostability, [6][7][8] and good solubility in various solvents, [9] exhibiting wide applications including dynamite, polyelectrolytes, [10,11] distinctive complex, [12] biocompatible material of different natures, and oxygen enriching membrane. [13][14][15] The investigation on the radical (co)polymerization, [16] radiation-induced bulk polymerization, [17] solution interdiffusion, [18,19] solution properties and kinetics of solution formation in various media, [20] rheological properties, [21] swelling thermodynamics, [22] and thermal degradation and its kinetics and mechanism of the PVT has been reported.…”