1996
DOI: 10.1002/(sici)1099-0895(199603)12:1<69::aid-dmr156>3.0.co;2-b
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Modification of Lipoproteins in Diabetes
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Cited by 34 publications
(11 citation statements)
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Section: Discussionmentioning
confidence: 99%
“……”
Section: Discussionmentioning
confidence: 99%
“…We have shown that LDL-IC metabolised by phagocytic cells (30) can activate the cell (29) which results in increased release of matrix metalloproteinases and pro-inflammatory cytokines which can contribute to unstable plaques and vascular inflammation, respectively (4). LDL-IC metabolism by phagocytic cells also leads to cholesteryl ester accumulation in the cell (1) which may be sufficient to result in foam cell formation. Collectively, these processes may both contribute to macrovascular disease in diabetes.…”
Section: Figures and Tablesmentioning
confidence: 99%
“…Oxidative modification of LDL results in rapid uptake by macrophages, which leads to foam cell formation and promotion of the expression of intercellular adhesion molecule-1 [45]. Furthermore, LDL oxidation in the postprandial state seems to be affected by an acute increase in glycemia.…”
Section: Postprandial Lipoproteins and Cvd Risks In Diabetic Populationsmentioning
confidence: 99%
