“…According to the JRDR analysis , a decrease in mortality rate with increasing Q B for up to 250–300 mL/min was suggested when 200 ≤ Q B < 220 mL/min was used as the reference. Although dialysis facilities in Japan are concerned about the increased load on the cardiovascular system with increasing Q B , an increase in blood flow of the vascular access or acute changes in cardiac function or blood pressure was not observed for 400 ≤ Q B < 500 mL/min . In fact, an increase in mortality rate was not observed for high‐efficiency dialysis performed even under Q B ≥ 400 mL/min .…”