Modification at the 2-Position of 4-Deoxypyridoxol and α⁴-Norpyridoxol

The Preparation of Someα4-Norpyridoxol Analogs

“…hydrochloride (1) A solution of NaN0 2 (0.4 g) in water (S ml) was added dropwise to a solution of VI (0.8 g) in 1 N HCI (60 ml) at 85°C. After the mixture was stirred at 85°C for 30 min, the solvent was removed and the residue was extracted with absolute EtOH.…”

Recent synthetic anticoccidial agents

“…activities were shown. T h e analogs(32) and(38) with acetyl and carbamoyl side chain abolished the activity. Branching, lengthening and shortening of the 5-hydroxymethyl group reduce the substrate activity.…”