Modificações no periodonto de ratos diabéticos após a movimentação ortodôntica

Real, Luis Alberto Sabino Vila; Ramos, Adilson Luiz; Zanoni, Jacqueline Nelisis

doi:10.1590/s1415-54192009000100012

Cited by 3 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4,6,13,14,18 Patients with type 1 DM are those who present greater susceptibility to microvascular alterations. 8 Studies related to dental movement and diabetes show that the disease promotes retarded osseous regeneration, 19 weakening of the periodontal ligament, 19 microangiopathies in the gingival area, 19,20 and larger and more severe bone gaps on the alveolar walls. 20 The reduced new-bone formation capacity is owing to the apoptosis of fibroblastic and osteoblastic cells in diabetic individuals.…”

Section: Discussionmentioning

confidence: 99%

“…8 Studies related to dental movement and diabetes show that the disease promotes retarded osseous regeneration, 19 weakening of the periodontal ligament, 19 microangiopathies in the gingival area, 19,20 and larger and more severe bone gaps on the alveolar walls. 20 The reduced new-bone formation capacity is owing to the apoptosis of fibroblastic and osteoblastic cells in diabetic individuals. 3 Case reports have been published on life-threatening deep neck infections from periodontal abscess 21 and fatal maxillary ulcers in patients with DM.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Maxillary ulceration resulting from using a rapid maxillary expander in a diabetic patient

Maia¹,

Monini²,

Jacob³

et al. 2011

The Angle Orthodontist

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Maxillary ulceration resulting from using a rapid maxillary expander in a diabetic patient

Maia¹,

Monini²,

Jacob³

et al. 2011

The Angle Orthodontist

View full text Add to dashboard Cite

“…Patients with type 1 DM are those who are more susceptible to microvascular changes 31 and studies related to tooth movement and DM show that the disease promotes delayed bone regeneration, weakened periodontal ligament 32 , microangiopathies in the gingival area 16,32 and larger and more severe gaps in the walls of the alveolar bone 16 . The capacity for new bone formation is reduced due to the apoptosis of fibroblastic and osteoblastic cells in diabetic individuals 33 .…”

Section: Diabetes Mellitusmentioning

confidence: 99%

“…Bone is a dynamic tissue that undergoes changes even after the end of skeletal growth, comprising the remodeling process, a balance between apposition and bone resorption. Orthodontic movement involves a series of biochemical changes that culminate in bone tissue reabsorption on the pressure side and apposition on the tension side, that is, orthodontic forces trigger a remodeling process promoting tooth movement 16 .…”

Section: Introductionmentioning

confidence: 99%

Biochemical and Immunological Interaction Between Diabetes Mellitus and Periodontal Diseases in Orthodontics Interação Bioquímica E Imunológica Entre a Diabetes Mellitus E Doenças Periondontais Na Ortodontia

Garcia¹,

Coutinho²,

Oliveira³

2021

RFO

View full text Add to dashboard Cite

Periodontal disease is complex once it involves disorders that affect the tissues. The main etiologic agent of the periodontium disease is the bacterial plaque and in its most advanced stages there might be loss of the teeth adhesion to the periodontal and the gingiva, with consequent local bone resorption, resulting in tooth loss. Diabetes mellitus is one of the most common chronic diseases in most countries and it is increasing in number and relevance. In 2019 was estimated that 463 million adults suffered from diabetes mellitus, a metabolic disorder known as being associated to various systemic diseases, as well as being associated with many problems in the oral areas. Studies have shown that diabetes, if untreated, can lead to the development of periodontal diseases. Several mechanisms have been suggested to explain the increased susceptibility to periodontal diseases, including changes in host response, subgingival microflora, gingival crevicular fluid and inheritance patterns. Multiple pathophysiological mechanisms are also associated with increased alveolar bone loss found in diabetic patients. The bidirectional inter-relationship between diabetes mellitus and periodontal diseases typifies a classic example of how a systemic disease can predispose to an oral infection and of how it can exacerbate a systemic condition.A doença periodontal é complexa, pois envolve distúrbios que afetam os tecidos. O principal agente etiológico da doença periodontal é a placa bacteriana e em seus estágios mais avançados pode haver perda da adesão dos dentes ao periodonto e gengiva, com consequente reabsorção óssea local, resultando em perda dentária. O diabetes mellitus é uma das doenças crônicas mais comuns na maioria dos países e está aumentando em número e relevância. Em 2019 foi estimado que 463 milhões de adultos sofreu com a diabetes mellitus, um distúrbio metabólico conhecido por estar associado a várias doenças sistêmicas, além de estar associado a diversos problemas nas áreas bucais. Estudos têm demonstrado que o diabetes, se não for tratado, pode levar ao desenvolvimento de doenças periodontais. Vários mecanismos têm sido sugeridos para explicar o aumento da suscetibilidade às doenças periodontais, incluindo mudanças na resposta do hospedeiro, microflora subgengival, fluido gengival e padrões de herança. Múltiplos mecanismos fisiopatológicos também estão associados à perda óssea alveolar aumentada encontrada em pacientes diabéticos. A inter-relação bidirecional entre diabetes mellitus e doenças periodontais tipifica um exemplo clássico de como uma doença sistêmica pode predispor a uma infecção oral e como pode exacerbar uma condição sistêmica.

show abstract

“…Além disso, o osso sofre alterações, mesmo após o final do crescimento do esqueleto, compreendendo o processo de remodelação, ou seja, um equilíbrio entre a aposição e a reabsorção óssea (REAL et al, 2009).…”

Section: Desenvolvimentounclassified

Os efeitos da atividade física na remodelação óssea

Soares

Filho

2017

J.Interdisc.Bio.

View full text Add to dashboard Cite

Bone is a dynamic tissue, developed and adapted by hormones, cytokines and mechanical stimuli, such as physical activity. The bone undergoes changes, even after the end of skeletal growth, comprising the remodeling process, that is a balance between apposition and bone reabsorption. In this context, the maintenance of bone mineral density (BMD) is very important for the prevention of metabolic bone diseases, such as osteoporosis, which is characterized by a marked decrease in BMD. Studies indicate that physical activity is positively related to BMD, being an important factor for its maintenance. Among these studies, some use force training as an intervention, in an attempt to increase the BMD of individuals submitted to this type of physical activity. At the cellular level, the process of remodeling induced by overload in physical activity, seems to be performed by the action of osteocytes, which act as mechanical receptors of the applied stress, and release a chemical stimulating factor of the proliferation of osteoblasts in the stressed place. This study aimed to evaluate the effect of physical activity on bone remodeling. For this purpose, information was searched in the databases of CAPES, MEDLINE, LILACS and in the SciELO virtual library, selecting papers published in national and international periodicals between 1999 and 2016. The descriptors of subjects used were: "physical activity "," Bone remodeling "," bone mineral density ", using the intersection of sets. Although some results are contradictory, the literature does not question the beneficial effects of physical activity on bone tissue, both in healthy individuals, and in the prevention and treatment of Osteoporosis. The mechanisms by which physical activity stimulates osteoblastic differentiation from bone marrow stromal cells should be better elucidated so that more appropriate therapies can be developed and used in the treatment of individuals with some metabolic bone disease. K E Y W O R D SMotor activity, Bone remodeling, Bone density R E S U M OO osso é um tecido dinâmico, desenvolvido e adaptado por hormônios, citocinas e estímulos mecânicos, como a atividade física. Ele sofre alterações, mesmo após o final do crescimento do esqueleto, compreendendo o processo de remodelação, ou seja, um equilíbrio entre a posição e reabsorção óssea. Nesse contexto, a manutenção da densidade mineral óssea (DMO) é muito importante para a prevenção de doenças ósseas metabólicas, como a osteoporose, a qual é caracterizada por uma diminuição acentuada da DMO. Estudos indicam que a atividade física está positivamente relacionada com a DMO, sendo um importante fator para sua manutenção. Dentre estes estudos, alguns utilizam o treinamento de força como intervenção, na tentativa de aumentar a DMO de indivíduos submetidos a esse tipo de atividade física. Em nível celular, o processo de remodelação, induzido pela sobrecarga, como na atividade física, parece ser realizado pela ação dos osteócitos, que atuam como receptores mecânicos do estresse aplicado e liberam um fa...

show abstract

Modificações no periodonto de ratos diabéticos após a movimentação ortodôntica

Cited by 3 publications

References 7 publications

Maxillary ulceration resulting from using a rapid maxillary expander in a diabetic patient

Maxillary ulceration resulting from using a rapid maxillary expander in a diabetic patient

Biochemical and Immunological Interaction Between Diabetes Mellitus and Periodontal Diseases in Orthodontics Interação Bioquímica E Imunológica Entre a Diabetes Mellitus E Doenças Periondontais Na Ortodontia

Os efeitos da atividade física na remodelação óssea

Contact Info

Product

Resources

About