Modic changes: “Age, si quid agis”

Franco, João Luiz Pinheiro

doi:10.1007/s00586-008-0804-9

Cited by 6 publications

(6 citation statements)

References 11 publications

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“…3,4,[14][15][16] Modic type I lesions are more often associated with low back pain than the other types and correspond to a hypervascular inflammatory state in which some degree of microinstability may exist. [4][5][6] This state of supposed instability may be a sign of active degeneration. 6 Type I lesions commonly progress to type II, but they also may go into remission.…”

Section: Discussionmentioning

confidence: 99%

“…[4][5][6] This state of supposed instability may be a sign of active degeneration. 6 Type I lesions commonly progress to type II, but they also may go into remission. 5,16 However, the morphological differences do not always correlate with the symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…15 Modic II is defined as a more stable state in which fat replacement is a continuation of the degenerative process. 6 Braithwaite et al report that the different Modic changes are the consequence of different states of the same pathology. 16,17 Several authors [4][5][6]8 indicate that the inflammatory lesions (I) are associated with SVI in 40% of cases and the degenerative lesions (II) in 20%.…”

Section: Discussionmentioning

confidence: 99%

“…6 Braithwaite et al report that the different Modic changes are the consequence of different states of the same pathology. 16,17 Several authors [4][5][6]8 indicate that the inflammatory lesions (I) are associated with SVI in 40% of cases and the degenerative lesions (II) in 20%. In our study we only analyzed the patients with Modic I (Groups A and B) and 11.63% of these patients presented SVI, a number less than that reported in the international literature.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 Modic type I lesions are more often associated with lumbar pain than the other types and correspond to a state of hypervascular inflammation, which may involve some degree of microinstability. [3][4][5][6] Lumbar spine instability is associated with lumbar pain and is strongly related to degenerative changes of the discs and joints and to the presence of morphological and structural changes of the yellow ligament; 1,2 and it is difficult to diagnose. 7 Evaluation using neutral lateral and anteroposterior radiographs is recommended in all patients with lumbar symptoms that persist for more than 4 to 6 weeks.…”

Section: Introductionmentioning

confidence: 99%

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Correlation Between the Modic I Sign and Images of Vertebral Instability

2021

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The lumbar region is highly affected by degenerative diseases and can be symptomatic as a result of inflammatory processes of the disc or segmental vertebral instability (SVI), according to concepts by White and Panjabi. Magnetic resonance imaging (MRI) and dynamic radiographs can be used to evaluate it. Objective: To determine whether images of Modic type I lesions are compatible with radiological vertebral instability. Methods: The MRIs and dynamic radiographs of 100 patients with a mean age of 46.94 years, 65 of whom were women and 35 of whom were men, were studied to evaluate the reaction of endplates according to Modic and SVI at levels L2-L3, L3-L4, L4-L5 and L5-S1. They were divided into 3 groups: A- Modic I and SVI; B- Modic I without SVI; and C- Without Modic I and SVI. Sex, age and type of disc were evaluated. Result: 46 Modic I lesions and 24 cases of SVI were recognized. There were 5 patients in Group A (OR 0.23, p=0.006), 38 in Group B; and 19 in Group C. No direct relationship between age and Modic I and/or SVI was observed. Pfirrmann grade 5 discs are 4.6 times more likely to present a Modic I signal. The most affected disc was L3-L4 for the Modic signal and L4-L5 with respect to the SVI, translational instability being more frequent. Conclusions: Modic type changes, identified by magnetic resonance, are clinically relevant in relation to low back pain, but their presence does not confirm either translational or angular instability. Level of evidence III; Cross-sectional cohort.

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